SCHEMBL335553

SCHEMBL335553

Cc1cccc(N2CCNCC2C)c1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 1/20 0.57
RAD52 P43351 1/20 0.49
GFER P55789 2/20 0.45
HTR2C P28335 4/20 0.44
HTR6 P50406 1/20 0.44
TSHR P16473 2/20 0.43
MAPT P10636 4/20 0.43
ALOX5 P09917 3/20 0.43
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
POLB P06746 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TP53 P04637 1/20 0.41
HTR2A P28223 3/20 0.41
HTR2B P41595 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23777738 1.00 ADRB1 (0.57) ADRB1RAD52GFERHTR2CHTR6
SCHEMBL30996886 1.00 ADRB1 (0.57) ADRB1RAD52GFERHTR2CHTR6
SCHEMBL23777830 1.00 ADRB1 (0.57) ADRB1RAD52GFERHTR2CHTR6
SCHEMBL27985661 0.83 RAD52 (0.47) ADRB1RAD52HTR2CHTR2AHTR2B
SCHEMBL27985663 0.83 RAD52 (0.47) ADRB1RAD52HTR2CHTR2AHTR2B
SCHEMBL5365024 0.83 ADRB1 (0.55) ADRB1HTR2CHTR6TSHRMAPT
SCHEMBL23777584 0.83 HTR2C (0.55) ADRB1RAD52HTR2CHTR6ALOX5
SCHEMBL23777573 0.83 RAD52 (0.45) ADRB1RAD52HTR2CALOX5HTR2A
SCHEMBL17884647 0.83 HTR2C (0.55) ADRB1RAD52HTR2CHTR6ALOX5
SCHEMBL2492032 0.83 RAD52 (0.48) RAD52HTR2CHTR2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8911775-B2 pH-sensitive block copolymer forming polyionic complex micelles and drug or protein carrier using the same SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE (KR) 2014-12-16 US claimed
EP-2340811-B1 Ph-sensitive block copolymer forming polyionic complex micelles and drug or protein carrier using the same UNIV SUNGKYUNKWAN FOUND (KR) 2014-10-15 EP claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
US-8835492-B2 Temperature and pH sensitive block copolymer and polymeric hydrogels using the same SUNGYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2014-09-16 US claimed
EP-1506176-B1 AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PFIZER ITALIA SRL (IT) 2013-04-24 EP claimed
US-8383153-B2 Poly(amidoamine) oligomer hydrogel for drug delivery and drug carrier using the same SUNGYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2013-02-26 US claimed
US-8318204-B2 pH sensitive block copolymer and polymeric micelle using the same SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2012-11-27 US claimed
US-20110217376-A1 POLY(AMIDOAMINE) OLIGOMER HYDROGEL FOR DRUG DELIVERY AND DRUG CARRIER USING THE SAME SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2011-09-08 US claimed
US-20100233264-A1 TEMPERATURE AND pH-SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT SAFTY IN VIVO AND HYDROGEL AND DRUG DELIVERY SYSTEM USING THEREOF SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2010-09-16 US claimed
WO-2009031861-A2 TEMPERATURE AND PH-SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT SAFETY IN VIVO AND HYDROGEL AND DRUG DELIVERY SYSTEM USING THEREOF SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2009-03-12 WO claimed
US-20080293827-A1 Temperature and Ph Sensitive Block Copolymer and Polymeric Hydrogels Using the Same SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR COROPORATE COLLABORATION (KR) 2008-11-27 US claimed
WO-2008130180-A1 PREPARATION OF DRUG DELIVERY SYSTEMS USING PH-SENSITIVE BLOCK COPOLYMER AND THEIR APPLICATION KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-10-30 WO claimed
US-20070218120-A1 Ph Sensitive Block Copolymer and Polymeric Micelle Using the Same SUNGKYUNKWAN UNIVERSITY FOUNDATIN FOR CORPORATE COLLOBORATION (KR) 2007-09-20 US claimed
US-20070179155-A1 N-phenyl-piperazine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases ARENA PHARMACEUTICALS, INC. 2007-08-02 US claimed
WO-2006109945-A1 TEMPERATURE AND PH SENSITIVE BLOCK COPOLYMER AND POLYMERIC HYDROGLES USING THE SAME SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2006-10-19 WO claimed
WO-2006098547-A1 PH SENSITIVE BLOCK COPOLYMER AND POLYMERIC MICELLE USING THE SAME SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2006-09-21 WO claimed
EP-1644347-A1 N-PHENYL-PIPERAZINE DERIVATIVES AND METHODS OF PROPHYLAXIS OR TREATMENT OF 5HT sb 2C /sb RECEPTOR ASSOCIATED DISEASES Arena Pharmaceuticals, Inc. (US) 2006-04-12 EP claimed
WO-2005016902-A1 N-PHENYL-PIPERAZINE DERIVATIVES AND METHODS OF PROPHYLAXIS OR TREATMENT OF 5HT2C RECEPTOR ASSOCIATED DISEASES ARENA PHARMACEUTICALS, INC. (US) 2005-02-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100233264-A1 TEMPERATURE AND pH-SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT SAFTY IN VIVO AND HYDROGEL AND DRUG DELIVERY SYSTEM USING THEREOF CD44, PSAT1, ALAD ADRB1 974/4885RAD52 1887/4885GFER 135/4885
US-20080293827-A1 Temperature and Ph Sensitive Block Copolymer and Polymeric Hydrogels Using the Same LRBA, DAO, PAM ADRB1 429/4885RAD52 2161/4885GFER 445/4885
US-20110217376-A1 POLY(AMIDOAMINE) OLIGOMER HYDROGEL FOR DRUG DELIVERY AND DRUG CARRIER USING THE SAME PAM, ACMSD, APEH ADRB1 2208/4885RAD52 1898/4885GFER 141/4885
US-20070218120-A1 Ph Sensitive Block Copolymer and Polymeric Micelle Using the Same PAM, DAO, PHYKPL ADRB1 838/4885RAD52 4295/4885GFER 1130/4885
US-20070179155-A1 N-phenyl-piperazine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases HTR2C, HTR2A, HTR5A ADRB1 49/4885RAD52 1733/4885GFER 2679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.