Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | TSHR | P16473 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | HTR1A | P08908 | 2/20 | 0.77 |
| ▸ | PKM | P14618 | 2/20 | 0.77 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | THPO | P40225 | 1/20 | 0.77 |
| ▸ | HTR2A | P28223 | 8/20 | 0.53 |
| ▸ | HTR7 | P34969 | 5/20 | 0.53 |
| ▸ | HTR6 | P50406 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6522324 | 0.92 | HTR2C (0.76) | HTR2CCYP2D6SMN1; SMN2CYP3A4MAPT | |
| Pirenperone SCHEMBL467209 | 0.87 | HTR2C (1.00) | HTR2CCYP2D6SMN1; SMN2CYP3A4MAPT | |
| Pirenperone SCHEMBL10965711 | 0.86 | HTR2C (0.98) | HTR2CCYP2D6SMN1; SMN2CYP3A4MAPT | |
| Pirenperone SCHEMBL10970070 | 0.84 | HTR2C (0.93) | HTR2CCYP2D6SMN1; SMN2CYP3A4MAPT | |
| Pirenperone SCHEMBL10967003 | 0.84 | HTR2C (0.93) | HTR2CCYP2D6SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL6527939 | 0.84 | HTR2C (0.77) | HTR2CCYP2D6SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL17532707 | 0.83 | CYP2D6 (0.86) | HTR2CCYP2D6SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL6518627 | 0.83 | ACHE (0.54) | HTR2CCYP2D6SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL6518635 | 0.83 | ACHE (0.54) | HTR2CCYP2D6SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL6518624 | 0.83 | ACHE (0.54) | HTR2CCYP2D6SMN1; SMN2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| EP-2252608-A1 | METHOD FOR TREATING PAIN SYNDROME AND OTHER DISORDERS | VM Discovery, Inc. (US) | 2010-11-24 | — | — | EP | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| WO-2009108798-A1 | METHOD FOR TREATING PAIN SYNDROME AND OTHER DISORDERS | VM DISCOVERY INC. (US) | 2009-09-03 | — | — | WO | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| EP-0268309-B1 | Serotonin antagonists for treating wounds | JANSSEN PHARMACEUTICA NV (BE) | 1996-12-11 | — | — | EP | claimed |
| US-4874766-A | TOPICALLY APPLYING SEROTONIN ANTAGONIST | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-10-17 | — | — | US | claimed |
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |
| US-11191719-B2 | Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration | STI PHARMA, LLC (US) | 2021-12-07 | — | — | US | disclosed |
| EP-3106166-B1 | COMPOUNDS FOR TREATING PAIN SYNDROME AND OTHER DISORDERS | VM THERAPEUTICS LLC (US) | 2020-12-02 | — | — | EP | disclosed |
| EP-3106166-B1 | COMPOUNDS FOR TREATING PAIN SYNDROME AND OTHER DISORDERS | VM THERAPEUTICS LLC (US) | 2020-12-02 | — | — | EP | disclosed |
| US-10471140-B2 | Composition for enhancing induction of humoral immunity, and vaccine pharmaceutical composition | NOTTO DENKO CORPORATION (JP) | 2019-11-12 | — | — | US | disclosed |
| US-4870060-A | SOLUBILIZERS FOR DRUGS | JANSSEN PHARMACEUTICA (BE) | 1989-09-26 | — | — | US | disclosed |
| US-4837168-A | QUALITATIVE, QUANTITATIVE ANALYSIS; VISUAL DETERMINATION | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-06-06 | — | — | US | disclosed |
| EP-0317001-A1 | A new universally applicable detection system based 0n ultra small colloidal metal particles | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-05-24 | — | — | EP | disclosed |
| US-4764604-A | Derivatives of gamma-cyclodextrin | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-08-16 | — | — | US | disclosed |
| EP-0197571-A2 | Novel derivatives of gamma-cyclodextrin | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-10-15 | — | — | EP | disclosed |