SCHEMBL6522324

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Metrenperone SCHEMBL2109868	0.92	HTR2C (0.77)	HTR2CCYP2D6CYP3A4MAPTTSHR
	SCHEMBL6527939	0.86	HTR2C (0.77)	HTR2CCYP2D6CYP3A4MAPTTSHR
	Pirenperone SCHEMBL467209	0.86	HTR2C (1.00)	HTR2CCYP2D6CYP3A4MAPTTSHR
	Pirenperone SCHEMBL10965711	0.85	HTR2C (0.98)	HTR2CCYP2D6CYP3A4MAPTTSHR
	Pirenperone SCHEMBL10970070	0.83	HTR2C (0.93)	HTR2CCYP2D6CYP3A4MAPTTSHR
	Pirenperone SCHEMBL10967003	0.83	HTR2C (0.93)	HTR2CCYP2D6CYP3A4MAPTTSHR
	Pirenperone SCHEMBL11242425	0.81	CYP2D6 (0.89)	HTR2CCYP2D6CYP3A4MAPTTSHR
	SCHEMBL10919317	0.81	HTR2C (0.73)	HTR2CCYP2D6CYP3A4MAPTTSHR
	SCHEMBL17532707	0.79	CYP2D6 (0.86)	HTR2CCYP2D6CYP3A4MAPTTSHR
	SCHEMBL10967011	0.78	CYP2D6 (0.86)	HTR2CCYP2D6CYP3A4MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.