Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21098985 | 0.88 | NPC1 (0.51) | NPC1RAB9AKMT2AALDH1A1TSHR | |
| SCHEMBL28209670 | 0.79 | KMT2A (0.64) | NPC1RAB9AKMT2AALDH1A1TSHR | |
| SCHEMBL20408443 | 0.75 | ALDH1A1 (0.55) | NPC1POLBCYP2C9RAB9AKMT2A | |
| SCHEMBL28397233 | 0.74 | KMT2A (0.48) | NPC1POLBRAB9AKMT2AALDH1A1 | |
| SCHEMBL16689961 | 0.72 | KMT2A (0.67) | NPC1POLBRAB9AKMT2AALDH1A1 | |
| SCHEMBL20679874 | 0.72 | NPC1 (0.55) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL3258075 | 0.71 | MEN1 (0.64) | NPC1POLBKMT2AALDH1A1HTT | |
| SCHEMBL14421372 | 0.71 | LMNA (0.55) | NPC1POLBCYP2C9RAB9AKMT2A | |
| SCHEMBL2612550 | 0.71 | SMN1; SMN2 (0.48) | POLBKMT2AALDH1A1TSHRNPSR1 | |
| SCHEMBL16689955 | 0.71 | SMPD1 (0.59) | NPC1POLBRAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323121-B2 | Poly-β-peptides from functionalized β-lactam monomers and antibacterial compositions containing same | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10323121-B2 | Poly-β-peptides from functionalized β-lactam monomers and antibacterial compositions containing same | TMSB10, TMSB4X, PTMA | NPC1 4188/4885POLB 1087/4885CYP2C9 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.