Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099008 | 0.88 | NPC1 (0.45) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL20679874 | 0.84 | NPC1 (0.55) | NPC1RAB9ANR4A2NR4A1NR4A3 | |
| SCHEMBL10392942 | 0.83 | KMT2A (0.65) | NPC1RAB9ANR4A2NR4A1NR4A3 | |
| SCHEMBL28209670 | 0.82 | KMT2A (0.64) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL13625842 | 0.81 | PRKCA (0.59) | NPC1RAB9ANR4A2NR4A1NR4A3 | |
| SCHEMBL6669799 | 0.81 | TDP1 (0.60) | NPC1RAB9ANR4A2NR4A1NR4A3 | |
| SCHEMBL11002185 | 0.79 | KMT2A (0.74) | NPC1RAB9ANR4A2KMT2AMEN1 | |
| SCHEMBL31715823 | 0.79 | TDP1 (0.69) | NPC1RAB9ANR4A2NR4A1NR4A3 | |
| SCHEMBL9509148 | 0.78 | NR4A2 (0.74) | NPC1RAB9ANR4A2NR4A1NR4A3 | |
| SCHEMBL8839073 | 0.78 | RXRA (0.68) | NPC1RAB9ANR4A2NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323121-B2 | Poly-β-peptides from functionalized β-lactam monomers and antibacterial compositions containing same | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10323121-B2 | Poly-β-peptides from functionalized β-lactam monomers and antibacterial compositions containing same | TMSB10, TMSB4X, PTMA | NPC1 4188/4885RAB9A 2680/4885NR4A2 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.