Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21098768 | 0.74 | ROCK2 (0.31) | — | |
| SCHEMBL21098760 | 0.72 | KDM4E (0.41) | KDM4EPOLB | |
| SCHEMBL21098736 | 0.70 | SMN1; SMN2 (0.35) | SMN1; SMN2ELANE | |
| SCHEMBL21098748 | 0.70 | KDM4E (0.36) | KDM4EPOLBSMN1; SMN2ESR1 | |
| SCHEMBL22787205 | 0.64 | — | — | |
| SCHEMBL21098681 | 0.64 | RXRA (0.41) | KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL21098937 | 0.63 | RXRA (0.41) | KDM4EPOLB | |
| SCHEMBL22787207 | 0.62 | MAOB (0.39) | SMN1; SMN2 | |
| SCHEMBL28490379 | 0.61 | ELANE (0.74) | KDM4EPOLBELANEESR1 | |
| SCHEMBL21098795 | 0.59 | MAOB (0.44) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019109188-A1 | ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2019-06-13 | — | — | WO | disclosed |