SCHEMBL2109976

SCHEMBL2109976

NOc1c(C(=O)O)cccc1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.58
BCAT2 O15382 1/20 0.52
FABP3 P05413 1/20 0.49
FABP4 P15090 1/20 0.49
FABP5 Q01469 1/20 0.49
MYC P01106 1/20 0.47
ALDH1A1 P00352 5/20 0.45
ALOX15 P16050 1/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSD17B10 Q99714 2/20 0.43
PTPN1 P18031 1/20 0.42
CHRNB2 P17787 1/20 0.42
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42
CHRNA4 P43681 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18143536 0.82 HNF4A (0.58) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL4632581 0.82 HNF4A (0.58) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL30394743 0.82 HNF4A (0.58) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL17799595 0.81 HNF4A (0.56) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL5798825 0.81 HNF4A (0.56) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL21646330 0.80 ALDH1A1 (0.48) HNF4ABCAT2ALDH1A1L3MBTL1HSD17B10
SCHEMBL11340527 0.79 HNF4A (0.54) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL10696832 0.79 HNF4A (0.54) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL28169509 0.79 HNF4A (0.54) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL1358288 0.79 KDM4E (0.63) HNF4ABCAT2FABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20220244263-A1 METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 US disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
CN-104546669-B Nanochannel device and correlation technique 得克萨斯大学体系董事会 2018-01-05 CN disclosed
CN-104546669-A NANOCHANNELED DEVICE AND RELATED METHODS UNIV TEXAS 2015-04-29 CN disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US disclosed
CN-102271732-B Nanochannel devices and related methods UNIV TEXAS 2014-12-31 CN disclosed
WO-2010024870-A1 SKIN-CONTACTING-ADHESIVE FREE DRESSING JENNINGS-SPRING BARBARA BROOKE (US) 2010-03-04 WO disclosed
US-20090005722-A1 Skin-contacting-adhesive free dressing JENNLNGS-SPRING BARBARA 2009-01-01 US disclosed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP disclosed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO disclosed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US disclosed
CN-1678188-A Nucleic acid compositions for modulating immune responses COLEY PHARM GROUP INC (US) 2005-10-05 CN disclosed
US-6326417-B1 CONTAINING SALICYLIC ACID COMPOUND AS MICROBIOCIDES JENERIC/PENTRON INCORPORATED 2001-12-04 US disclosed
US-4036951-A SUNSCREEN AGENTS SYNERGISTICS, INC. (US) 1977-07-19 US disclosed