Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18892609 | 0.82 | KIF11 (0.50) | SLC6A4KDM4EHSD17B10TSHRLMNA | |
| SCHEMBL22297610 | 0.81 | SLC6A4 (0.37) | SLC6A4KDM4EHSD17B10TSHRLMNA | |
| SCHEMBL10871691 | 0.81 | HPGD (0.73) | SLC6A4MAPK1HPGDLMNAL3MBTL1 | |
| SCHEMBL13923556 | 0.80 | SLC6A4 (0.47) | SLC6A4KDM4EHSD17B10ARHTT | |
| SCHEMBL333951 | 0.80 | SLC6A4 (0.47) | SLC6A4KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL18892640 | 0.78 | RAB9A (0.52) | SLC6A4KDM4EMAPK1TSHRHPGD | |
| SCHEMBL2737144 | 0.78 | SLC6A4 (0.45) | SLC6A4KDM4EHSD17B10MAPK1CYP3A4 | |
| SCHEMBL15063439 | 0.78 | SLC6A4 (0.45) | SLC6A4KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL5546729 | 0.78 | SLC6A4 (0.45) | SLC6A4KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL7937564 | 0.78 | SLC6A4 (0.45) | SLC6A4KDM4EHSD17B10MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329451-B2 | All-organic high refractive index materials | BREWER SCIENCE, INC. (US) | 2019-06-25 | — | — | US | disclosed |