Salazosulfamide

Salazosulfamide

SCHEMBL2110085

NS(=O)(=O)c1ccc(N=Nc2ccc(O)c(C(=O)O)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 1.00
PTGS1 P23219 5/20 1.00
PHLPP2 Q6ZVD8 5/20 1.00
ALDH1A1 P00352 3/20 1.00
CYP2C9 P11712 2/20 1.00
HSD17B10 Q99714 1/20 1.00
GLO1 Q04760 2/20 0.76
MEN1 O00255 4/20 0.72
KMT2A Q03164 4/20 0.72
BLVRB P30043 2/20 0.72
PDE4A P27815 1/20 0.72
KDR P35968 1/20 0.72
HTT P42858 1/20 0.72
TDP1 Q9NUW8 3/20 0.69
APP P05067 1/20 0.69
THRB P10828 1/20 0.69
RECQL P46063 1/20 0.69
BLM P54132 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.62
CA2 P00918 3/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salazosulfamide SCHEMBL6432001 1.00 PTGS2 (1.00) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
Salazosulfamide SCHEMBL11884576 0.91 PHLPP2 (0.82) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
SCHEMBL14596773 0.88 PHLPP2 (0.78) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
SCHEMBL6250400 0.88 PHLPP2 (0.78) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
SCHEMBL5576043 0.88 PHLPP2 (0.78) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
SCHEMBL30604557 0.88 PHLPP2 (0.78) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
Olsalazine SCHEMBL5922630 0.87 MEN1 (0.96) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
SCHEMBL27727542 0.86 PHLPP2 (0.76) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
Olsalazine SCHEMBL25119 0.85 MEN1 (1.00) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
Olsalazine SCHEMBL25118 0.85 MEN1 (1.00) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101277684-A Microparticles for the modified release of at least one active principle and oral pharmaceutical forms containing them FLAMEL TECH SA (FR) 2008-10-01 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
CN-101237838-A Combination therapy for the treatment of immunoinflammatory disorders COMBINATORX INC (US) 2008-08-06 CN claimed
CN-101203509-A Amine-linked pyridyl and phenyl substituted piperazine-piperidines with CXCR3 antagonist activity SCHERING CORP (US) 2008-06-18 CN claimed
CN-101189238-A Piperazine-piperidines with CXCR3 antagonist activity SCHERING CORP (US) 2008-05-28 CN claimed
CN-101189225-A Heteroaryl substituted pyrazinyl-piperazine-piperidines with CXCR3 antagonist activity SCHERING CORP (US) 2008-05-28 CN claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20050080260-A1 Preparation of prodrugs for selective drug delivery LUMINIDE 2005-04-14 US claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
US-6159585-A Security paper GEORGIA-PACIFIC CORPORATION (US) 2000-12-12 US claimed
WO-1998041688-A1 SECURITY PAPER GEORGIA-PACIFIC CORPORATION, INC. (US) 1998-09-24 WO claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP disclosed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080260-A1 Preparation of prodrugs for selective drug delivery APEH, PAH, ALAD PTGS2 2698/4885PTGS1 2771/4885PHLPP2 732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.