Salazosulfamide

Salazosulfamide

SCHEMBL6432001

NS(=O)(=O)c1ccc(/N=N/c2ccc(O)c(C(=O)O)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 1.00
PTGS1 P23219 5/20 1.00
PHLPP2 Q6ZVD8 5/20 1.00
ALDH1A1 P00352 3/20 1.00
CYP2C9 P11712 2/20 1.00
HSD17B10 Q99714 1/20 1.00
GLO1 Q04760 2/20 0.76
MEN1 O00255 4/20 0.72
KMT2A Q03164 4/20 0.72
BLVRB P30043 2/20 0.72
PDE4A P27815 1/20 0.72
KDR P35968 1/20 0.72
HTT P42858 1/20 0.72
TDP1 Q9NUW8 3/20 0.69
APP P05067 1/20 0.69
THRB P10828 1/20 0.69
RECQL P46063 1/20 0.69
BLM P54132 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.62
CA2 P00918 3/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salazosulfamide SCHEMBL2110085 1.00 PTGS2 (1.00) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
Salazosulfamide SCHEMBL11884576 0.91 PHLPP2 (0.82) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
SCHEMBL14596773 0.88 PHLPP2 (0.78) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
SCHEMBL6250400 0.88 PHLPP2 (0.78) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
SCHEMBL5576043 0.88 PHLPP2 (0.78) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
SCHEMBL30604557 0.88 PHLPP2 (0.78) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
Olsalazine SCHEMBL5922630 0.87 MEN1 (0.96) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
SCHEMBL27727542 0.86 PHLPP2 (0.76) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
Olsalazine SCHEMBL25119 0.85 MEN1 (1.00) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9
Olsalazine SCHEMBL25118 0.85 MEN1 (1.00) PTGS2PTGS1PHLPP2ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10695830-B2 Copper powder, copper paste using same, conductive coating material, conductive sheet, and method for producing copper powder SUMITOMO METAL MINING CO., LTD. (JP) 2020-06-30 US disclosed
US-10654101-B2 Silver-coated copper powder, copper paste using same, conductive coating material, conductive sheet, and method for producing silver-coated copper powder SUMITOMO METAL MINING CO., LTD. (JP) 2020-05-19 US disclosed
CN-107614156-B Copper powder and the manufacturing method for using its copper cream, conductive coating paint, conductive sheet and copper powder 住友金属矿山株式会社 2019-10-25 CN disclosed
CN-107708893-B Silver-coated copper powder, copper paste using same, conductive coating material, conductive sheet, and method for producing silver-coated copper powder 住友金属矿山株式会社 2019-09-27 CN disclosed
US-20180154436-A1 SILVER-COATED COPPER POWDER, COPPER PASTE USING SAME, CONDUCTIVE COATING MATERIAL, CONDUCTIVE SHEET, AND METHOD FOR PRODUCING SILVER-COATED COPPER POWDER SUMITOMO METAL MINING CO., LTD. (JP) 2018-06-07 US disclosed
US-20180111190-A1 COPPER POWDER, COPPER PASTE USING SAME, CONDUCTIVE COATING MATERIAL, CONDUCTIVE SHEET, AND METHOD FOR PRODUCING COPPER POWDER SUMITOMO METAL MINING CO., LTD. (JP) 2018-04-26 US disclosed
EP-3296042-A1 SILVER-COATED COPPER POWDER, COPPER PASTE USING SAME, CONDUCTIVE COATING MATERIAL, CONDUCTIVE SHEET, AND METHOD FOR PRODUCING SILVER-COATED COPPER POWDER Sumitomo Metal Mining Co., Ltd. (JP) 2018-03-21 EP disclosed
EP-3296041-A1 COPPER POWDER, COPPER PASTE USING SAME, CONDUCTIVE COATING MATERIAL, CONDUCTIVE SHEET, AND METHOD FOR PRODUCING COPPER POWDER Sumitomo Metal Mining Co., Ltd. (JP) 2018-03-21 EP disclosed
CN-107708893-A Silver-Coated Copper Powder, Copper Paste Using Same, Conductive Coating Material, Conductive Sheet, And Method For Producing Silver-Coated Copper Powder 住友金属矿山株式会社 2018-02-16 CN disclosed
CN-107614156-A Copper powder and the manufacture method using its copper cream, conductive coating paint, conductive sheet and copper powder 住友金属矿山株式会社 2018-01-19 CN disclosed
US-20050080260-A1 Preparation of prodrugs for selective drug delivery LUMINIDE 2005-04-14 US disclosed
US-6555663-B1 Pharmaceuticals which are activated intracellularly by reaction with cellular electron carriers or free radicals to cause release of a free and active drug molecule MILLS RANDELL LEE (US) 2003-04-29 US disclosed
EP-0414730-B1 Chemical Compounds and pharmaceutical compositions capable of releasing a drug MILLS RANDELL L (US) 1999-12-15 EP disclosed
US-5773592-A COMPRISES A CHEMILUMINESCENT MOIETY, A PHOTOCHROMIC MOIETY AND A BIOLOGICALLY ACTIVE AGENT CAPABLE OF BEING RELEASED MILLS RANDELL LEE (US) 1998-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080260-A1 Preparation of prodrugs for selective drug delivery APEH, PAH, ALAD PTGS2 2698/4885PTGS1 2771/4885PHLPP2 732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.