Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 10/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21479563 | 0.84 | ABCG2 (0.40) | ABCG2ABCB1SUCNR1L3MBTL1CA1 | |
| SCHEMBL17919158 | 0.79 | FAAH (0.44) | ABCG2ABCB1SUCNR1L3MBTL1CA1 | |
| SCHEMBL21100864 | 0.79 | FAAH (0.44) | ABCG2ABCB1SUCNR1L3MBTL1CA1 | |
| SCHEMBL17919107 | 0.79 | CA1 (0.50) | ADRB2SUCNR1LMNAITGB3ITGA2B | |
| SCHEMBL21479482 | 0.77 | CA1 (0.40) | ABCG2ABCB1SUCNR1CA1CA2 | |
| SCHEMBL13820229 | 0.77 | HDAC8 (0.45) | ABCG2HDAC8LMNAKMT2A | |
| SCHEMBL13764449 | 0.77 | HDAC8 (0.45) | ABCG2HDAC8LMNAKMT2A | |
| SCHEMBL15849827 | 0.77 | HDAC8 (0.45) | ABCG2HDAC8LMNAKMT2A | |
| SCHEMBL18069670 | 0.75 | ABCG2 (0.41) | ABCG2HDAC8ABCB1LMNACA1 | |
| SCHEMBL17282260 | 0.74 | ITGB3 (0.63) | HDAC8SUCNR1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10328043-B1 | Composition and method for dual targeting in treatment of neuroendocrine tumors | NANOPHARMACEUTICALS, LLC. (US) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10328043-B1 | Composition and method for dual targeting in treatment of neuroendocrine tumors | THRB, TSHR, SLC6A2 | ABCG2 673/4885HDAC8 2804/4885ADRB2 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.