Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | INPPL1 | O15357 | 3/20 | 0.33 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | IDUA | P35475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21101084 | 0.86 | THRB (0.34) | THRBTSHRHPGDBLMALDH1A1 | |
| SCHEMBL10608569 | 0.80 | THRB (0.44) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL28458287 | 0.79 | THRB (0.48) | THRBTSHRHPGDBLMALDH1A1 | |
| SCHEMBL14679866 | 0.79 | THRB (0.43) | THRBTSHRHPGDBLMALDH1A1 | |
| SCHEMBL14341772 | 0.79 | THRB (0.43) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL9174872 | 0.78 | THRB (0.57) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL4292409 | 0.75 | SRC (0.47) | TSHRBLMALDH1A1HIF1ASRC | |
| SCHEMBL13223073 | 0.73 | ALDH1A1 (0.45) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL15003869 | 0.73 | THRB (0.38) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL279036 | 0.73 | CA12 (0.46) | TSHRHPGDBLMALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10322069-B2 | Restorative resin compositions and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-06-18 | — | — | US | disclosed |