Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 5/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709550 | 0.85 | EGFR (0.41) | BLMEGFRERBB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL20315400 | 0.81 | BLM (0.50) | SRCBLMEGFRERBB2SMN1; SMN2 | |
| SCHEMBL20107974 | 0.78 | BLM (0.40) | SRCBLMALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL9151493 | 0.77 | LMNA (0.61) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL329313 | 0.76 | SRC (0.75) | SRCBLMSMN1; SMN2TSHRCA1 | |
| SCHEMBL8508241 | 0.75 | EGFR (0.47) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL21100916 | 0.75 | THRB (0.41) | SRCBLMALDH1A1HIF1ATSHR | |
| SCHEMBL10686398 | 0.74 | EGFR (0.50) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL7717389 | 0.74 | ALDH1A1 (0.50) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL5384052 | 0.74 | CYP3A4 (0.49) | EGFRERBB2ALDH1A1SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206962-A1 | RECOMBINANT ONCOLYTIC VIRUS AND MEDICAL USE THEREOF | 深圳艾欣达伟医药科技有限公司 | 2022-10-06 | — | — | WO | disclosed |
| US-8257918-B2 | Intelligent nanomedicine integrating diagnosis and therapy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-09-04 | — | — | US | disclosed |
| US-20100010094-A1 | Novel nitrophenyl mustard and nitrophenylaziridine alcohols and their corresponding phosphates and their use as targeted cytotoxic agents | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-01-14 | — | — | US | disclosed |
| US-7629332-B2 | Nitrophenyl mustard and nitrophenylaziridine alcohols and their corresponding phosphates and their use as targeted cytotoxic agents | AUCKLAND UNISERVICES LIMITED (NZ) | 2009-12-08 | — | — | US | disclosed |
| US-20090202507-A1 | Intelligent Nanomedicine Integrating Diagnosis And Therapy | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS) (US) | 2009-08-13 | — | — | US | disclosed |
| US-20070032455-A1 | Novel nitrophenyl mustard and nitrophenylaziridine alcohols and their corresponding phosphates and their use as targeted cytotoxic agents | AUCKLAND UNIVERVICES LIMITED (NZ) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032455-A1 | Novel nitrophenyl mustard and nitrophenylaziridine alcohols and their corresponding phosphates and their use as targeted cytotoxic agents | NAPRT, NTPCR, PNP | SRC 3548/4885BLM 4792/4885EGFR 2171/4885 |
| US-20100010094-A1 | Novel nitrophenyl mustard and nitrophenylaziridine alcohols and their corresponding phosphates and their use as targeted cytotoxic agents | NAPRT, NTPCR, QDPR | SRC 3512/4885BLM 4766/4885EGFR 2370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.