Glycerin

Glycerin

SCHEMBL21101

O=P(O)(O)O.OCC(O)CO

nearest known ligand 0.64

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.64
ALDH1A1 P00352 1/20 0.64
THRB P10828 2/20 0.42
GABRR1 P24046 1/20 0.36
GABBR2 O75899 1/20 0.36
GABBR1 Q9UBS5 1/20 0.36
KDM4E B2RXH2 1/20 0.33
MMP2 P08253 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
OR51E2 Q9H255 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
AKR1B1 P15121 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ANPEP P15144 1/20 0.30
ERAP2 Q6P179 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL30710214 1.00 LMNA (0.64) LMNAALDH1A1THRBGABRR1GABBR2
Glycerin SCHEMBL31106042 1.00 LMNA (0.64) LMNAALDH1A1THRBGABRR1GABBR2
Glycerin SCHEMBL888512 1.00 LMNA (0.64) LMNAALDH1A1THRBGABRR1GABBR2
Glycerin SCHEMBL579432 1.00 LMNA (0.64) LMNAALDH1A1THRBGABRR1GABBR2
Glycerin SCHEMBL188342 1.00 LMNA (0.64) LMNAALDH1A1THRBGABRR1GABBR2
Glycerin SCHEMBL468814 0.97 LMNA (0.60) LMNAALDH1A1THRBGABRR1GABBR2
Glycerin SCHEMBL1792712 0.97 LMNA (0.60) LMNAALDH1A1THRBGABRR1GABBR2
Glycerin SCHEMBL14482187 0.97 LMNA (0.60) LMNAALDH1A1THRBGABRR1GABBR2
Glycerin SCHEMBL14482185 0.97 LMNA (0.60) LMNAALDH1A1THRBGABRR1GABBR2
Glycerin SCHEMBL9332836 0.97 LMNA (0.60) LMNAALDH1A1THRBGABRR1GABBR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6263 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-12625104-B2 Method for improving stability of electrochemical sensor PEKING UNIVERSITY (CN) 2026-05-12 US claimed
US-20260009044-A1 FERMENTATIVE GLYCEROL-FREE ETHANOL PRODUCTION DSM IP ASSETS BV (NL) 2026-01-08 US claimed
US-12449415-B2 Diagnostics QUEEN MARY UNIVERSITY OF LONDON (GB) 2025-10-21 US claimed
US-12435339-B2 Fermentative glycerol-free ethanol production DSM IP ASSETS B.V. (NL) 2025-10-07 US claimed
EP-4622648-A1 SELECTION OF PATIENTS FOR THE TREATMENT OF FADS1-MEDIATED DISEASES OR DISORDERS USING FADS-1 INHIBITORS Amgen Inc. (US) 2025-10-01 EP claimed
US-20250283121-A1 RECOMBINANT YEAST CELL DANISCO US INC (US) 2025-09-11 US claimed
US-20250277240-A1 RECOMBINANT YEAST CELL DANISCO US INC (US) 2025-09-04 US claimed
US-20250163361-A1 RECOMBINANT YEAST CELL DANISCO US INC (US) 2025-05-22 US claimed
US-4469635-A EMULSIFIERS THE PROCTER & GAMBLE COMPANY (US) 1984-09-04 US claimed
EP-0100217-A2 Process for quantitative determination of substrate treated with oxidase WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1984-02-08 EP claimed
EP-0072581-A1 The stabilization of working reagent solutions containing enzymes, and the use of such stabilized reagents in enzyme or substrate assays American Monitor Corporation (US) 1983-02-23 EP claimed
US-4372874-A Stabilization of hydrolysis prone labile organic reagents in liquid media MEDICAL ANALYSIS SYSTEMS, INC. 1983-02-08 US claimed
US-4368261-A IN PRESENCE OF GLYCEROL KINASE FROM BACILLUS STEAROTHERMOPHILIS BOEHRINGER MANNHEIM GMBH (DE) 1983-01-11 US claimed
US-4242446-A Method for determining a substance in a biological fluid and reagent combination for use in the method COULTER ELECTRONICS, INC. (US) 1980-12-30 US claimed
EP-0009222-A2 The stabilization of working reagent solutions containing NADH, NADPH, and/or enzymes, and the use of such stabilized reagents in enzyme or substrate assays American Monitor Corp. (US) 1980-04-02 EP claimed
EP-0006582-A2 Method for stabilizing solutions of gamma-glutamyl-p-nitroanilide Modrovich, Ivan Endre (US) 1980-01-09 EP claimed
US-4172032-A Polyphosphate-based industrial cooling water treatment NALCO CHEMICAL COMPANY (US) 1979-10-23 US claimed
US-4168230-A Synergistic composition comprising phosphorylated ethoxylated glycerine and polyacrylic acid for the prevention of CaCO3 scale in cooling water NALCO CHEMICAL COMPANY (US) 1979-09-18 US claimed