Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL30710214 | 1.00 | LMNA (0.64) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL31106042 | 1.00 | LMNA (0.64) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL888512 | 1.00 | LMNA (0.64) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL188342 | 1.00 | LMNA (0.64) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL21101 | 1.00 | LMNA (0.64) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL468814 | 0.97 | LMNA (0.60) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL1792712 | 0.97 | LMNA (0.60) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL14482187 | 0.97 | LMNA (0.60) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL14482185 | 0.97 | LMNA (0.60) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL9332836 | 0.97 | LMNA (0.60) | LMNAALDH1A1THRBGABRR1GABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12628820-B2 | Systems and methods for preservation of cells | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2026-05-19 | — | — | US | claimed |
| CN-122060467-A | Modified nano plugging agent, drilling fluid and preparation method thereof | 中国石油天然气股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| US-20260132436-A9 | COMPOSITIONS AND METHODS FOR RNA SYNTHESIS | HELIX NANOTECHNOLOGIES INC (US) | 2026-05-14 | — | — | US | claimed |
| US-20250223621-A1 | COMPOSITIONS AND METHODS FOR RNA SYNTHESIS | HELIX NANOTECHNOLOGIES INC | 2025-07-10 | — | — | US | claimed |
| EP-4548942-A2 | METHODS FOR PRESERVATION OF CELLS | University Of Louisville Research Foundation, Inc. (US) | 2025-05-07 | — | — | EP | claimed |
| EP-4543826-A1 | MICROBE-ENHANCED FERTILIZERS | Sabic Agri-Nutrients Company (SA) | 2025-04-30 | — | — | EP | claimed |
| CN-119585231-A | Microbial enhanced fertilizer | 沙特基础工业公司农业营养素 | 2025-03-07 | — | — | CN | claimed |
| EP-3638021-B1 | METHODS FOR PRESERVATION OF CELLS | UNIV OF LOUISVILLE RESEARCH FOUNDATION (US) | 2025-01-22 | — | — | EP | claimed |
| US-12139734-B2 | Compositions and methods for RNA synthesis | HELIX NANOTECHNOLOGIES INC (US) | 2024-11-12 | — | — | US | claimed |
| WO-2024135187-A1 | METHOD AND DEVICE FOR MANUFACTURING COMPATIBLE SOLUTE | 国立大学法人東京農工大学 | 2024-06-27 | — | — | WO | claimed |
| EP-2430195-A2 | COMPOSITIONS AND METHODS FOR BIOLOGICAL SAMPLE STORAGE | Biomatrica, INC. (US) | 2012-03-21 | — | — | EP | claimed |
| WO-2011120872-A2 | STABILIZED BIO-AVAILABLE SOLUBLE SILICATE SOLUTION | TAMINCO (BE) | 2011-10-06 | — | — | WO | claimed |
| EP-2371220-A1 | Stabilized bio-available soluble silicate solution | Taminco (BE) | 2011-10-05 | — | — | EP | claimed |
| US-20110081363-A1 | COMPOSITIONS AND METHODS FOR BIOLOGICAL SAMPLE STORAGE | BIOMATRICA, INC. (US) | 2011-04-07 | — | — | US | claimed |
| WO-2010132508-A2 | COMPOSITIONS AND METHODS FOR BIOLOGICAL SAMPLE STORAGE | BIOMATRICA, INC. (US) | 2010-11-18 | — | — | WO | claimed |
| EP-1311238-B1 | USE OF DI-SUGAR ALCOHOL PHOSPHATES TO PROTECT HUMAN SKIN CELLS FROM UV-AND/OR IR RADIATION | BITOP GMBH (DE) | 2009-10-21 | — | — | EP | claimed |
| US-20070122464-A1 | Use of osmolytes obtained from extremophilic bacteria for producing medicine for the external treatment of neurodermatitis | BITOP AG (DE) | 2007-05-31 | — | — | US | claimed |
| US-20060246007-A1 | Use of osmolytes obtained from extremophilic bacteria the production of inhalable medicaments for the prophylaxis and treatment of pulmonary and cardiovascular diseases and an inhalation device comprising an osmolyte as active agent component | BITOP AKTIENGESELLSCHAFT FUR BIOTECHNISCHE OPTIMIERUNG (DE) | 2006-11-02 | — | — | US | claimed |
| US-20030114358-A1 | Use of compatible solutes as inhibitors of the enzymatic decomposition of macromolecular biopolymers | BITOP GESELLSCHAFT FUR BIOTECHNISCHE OPTIMLERUNG MBH (DE) | 2003-06-19 | — | — | US | claimed |
| EP-0965268-A1 | Thermostabilization, osmoprotection, and protection against desiccation of enzymes, cell components and cells by di-glycerol-phosphate | IBET - Instituto de Biologia Experimental e Tecnologica (PT) | 1999-12-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110081363-A1 | COMPOSITIONS AND METHODS FOR BIOLOGICAL SAMPLE STORAGE | DNASE1, DIS3, NEFM | LMNA 72/4885ALDH1A1 4251/4885THRB 3507/4885 |
| US-12628820-B2 | Systems and methods for preservation of cells | IPMK, PHOSPHO1, ITPA | LMNA 85/4885ALDH1A1 4221/4885THRB 314/4885 |
| US-20260132436-A9 | COMPOSITIONS AND METHODS FOR RNA SYNTHESIS | RNGTT, RNMT, POLRMT | LMNA 596/4885ALDH1A1 3994/4885THRB 3206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.