Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4426342 | 0.90 | DRD2 (0.48) | DRD2DRD3KDM4EALDH1A1MAPT | |
| SCHEMBL4420854 | 0.85 | DRD2 (0.51) | DRD2DRD3KDM4EALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL4429607 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1MAPTHSD17B10AVPR1A | |
| SCHEMBL1727741 | 0.78 | CHRM4 (0.56) | DRD2DRD3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL4704844 | 0.77 | DRD2 (0.51) | DRD2DRD3KDM4EALDH1A1MAPT | |
| SCHEMBL4429602 | 0.77 | DRD2 (0.51) | DRD2DRD3KDM4EALDH1A1MAPT | |
| SCHEMBL28972659 | 0.76 | KCNH2 (0.60) | DRD2DRD3POLB | |
| SCHEMBL4417334 | 0.75 | GPR119 (0.59) | DRD2KDM4EALDH1A1HSD17B10CHRM4 | |
| SCHEMBL17960725 | 0.75 | DRD2 (0.41) | DRD2DRD3KDM4EALDH1A1MAPT | |
| SCHEMBL27608623 | 0.75 | AVPR1A (0.47) | DRD2DRD3KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |