Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | TERT | O14746 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20077346 | 0.76 | MAPT (0.38) | MAPTADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL1031945 | 0.76 | MAPT (0.38) | MAPTMAP4K4 | |
| SCHEMBL19965851 | 0.75 | CCR1 (0.52) | MAPT | |
| SCHEMBL5801735 | 0.75 | ADRA2A (0.42) | MAPTADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL23485338 | 0.75 | FGFR3 (0.50) | — | |
| SCHEMBL29984917 | 0.75 | FGFR3 (0.50) | — | |
| SCHEMBL9374249 | 0.71 | CCR1 (0.60) | — | |
| SCHEMBL3583880 | 0.68 | KDM4E (0.49) | MAPTCCNB2CDK1CCNB1CDK5 | |
| SCHEMBL19932239 | 0.68 | MAPT (0.41) | MAPT | |
| SCHEMBL26194060 | 0.67 | MAPT (0.48) | MAPTADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210984-B1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2019-06-19 | — | — | EP | disclosed |