Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.39 |
| ▸ | NFKBIA | P25963 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776759 | 0.77 | NOS3 (0.39) | CCR1RAB9ACCR5LMNAKDM4E | |
| SCHEMBL10309544 | 0.76 | LMNA (0.59) | CCR1RAB9ACCR5GLO1METAP2 | |
| SCHEMBL23192966 | 0.75 | CCR1 (0.61) | CCR1RAB9ACCR5GLO1METAP2 | |
| SCHEMBL7453433 | 0.75 | CCR1 (0.61) | CCR1RAB9ACCR5GLO1METAP2 | |
| SCHEMBL21101408 | 0.75 | MAPT (0.36) | MAPT | |
| SCHEMBL26307346 | 0.74 | GLO1 (0.62) | CCR1RAB9ACCR5GLO1METAP2 | |
| SCHEMBL20838492 | 0.74 | CCR1 (0.58) | CCR1RAB9ACCR5GLO1METAP2 | |
| SCHEMBL9374249 | 0.73 | CCR1 (0.60) | CCR1CCR5SLC40A1NFKBIAPARP1 | |
| Neocuproine SCHEMBL4394429 | 0.71 | CCR1 (0.88) | CCR1RAB9ACCR5GLO1METAP2 | |
| Neocuproine SCHEMBL2415313 | 0.71 | CCR1 (0.88) | CCR1RAB9ACCR5GLO1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570156-B2 | Substituted imidazo[1,2-a]pyridines as PDE-10 inhibitors | SUNOVION PHARMACEUTICALS INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20180072759-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072759-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | COMT, GPR119, NLN | CCR1 3722/4885RAB9A 957/4885CCR5 4191/4885 |
| US-10570156-B2 | Substituted imidazo[1,2-a]pyridines as PDE-10 inhibitors | PDE3A, PDE2A, PDE5A | CCR1 2639/4885RAB9A 595/4885CCR5 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.