Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.60 |
| ▸ | CCR5 | P51681 | 2/20 | 0.60 |
| ▸ | CCR8 | P51685 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NCK1 | P16333 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374219 | 0.81 | BACE1 (0.37) | CCR1CCR5CCR8KDM4EBACE1 | |
| SCHEMBL30492603 | 0.77 | CCR1 (1.00) | CCR1CCR5CCR8KDM4EPSMD14 | |
| SCHEMBL686948 | 0.77 | CCR1 (1.00) | CCR1CCR5CCR8KDM4EPSMD14 | |
| SCHEMBL9378650 | 0.75 | CCR1 (0.64) | CCR1CCR5CCR8KDM4EPSMD14 | |
| SCHEMBL19965851 | 0.73 | CCR1 (0.52) | CCR1CCR5KDM4EPARP1SLC40A1 | |
| SCHEMBL10309544 | 0.71 | LMNA (0.59) | CCR1CCR5CCR8KDM4EPSMD14 | |
| SCHEMBL21101408 | 0.71 | MAPT (0.36) | — | |
| SCHEMBL9030070 | 0.71 | CCR1 (0.58) | CCR1CCR5CCR8KDM4EPSMD14 | |
| SCHEMBL27103553 | 0.70 | CCR1 (0.57) | CCR1CCR5CCR8KDM4EPSMD14 | |
| SCHEMBL15426480 | 0.70 | NOS3 (0.56) | CCR1CCR5CCR8KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401582-B1 | Quinoline derivatives condensed with five-membered heterocyclic rings | BASF AG (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5167695-A | Pre- and postemergence herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-01 | — | — | US | disclosed |