Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21101503 | 0.88 | ALDH1A1 (0.32) | HPGDMAPTTP53ALDH1A1HSD17B10 | |
| SCHEMBL17570822 | 0.88 | PLA2G2A (0.38) | HPGDMAPTTP53ALDH1A1CYP3A4 | |
| SCHEMBL12799784 | 0.73 | HPGD (0.54) | HPGDMAPTTP53ALDH1A1CYP3A4 | |
| SCHEMBL21101412 | 0.72 | HPGD (0.40) | HPGDMAPTTP53ALDH1A1CYP3A4 | |
| SCHEMBL12799772 | 0.70 | MAPT (0.59) | HPGDMAPTTP53ALDH1A1CYP3A4 | |
| SCHEMBL19521810 | 0.69 | MAPT (0.50) | HPGDMAPTTP53ALDH1A1CYP3A4 | |
| SCHEMBL9917111 | 0.68 | L3MBTL1 (0.49) | HPGDMAPTTP53ALDH1A1CYP3A4 | |
| SCHEMBL21429587 | 0.67 | KMT2A (0.36) | HPGDMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL9917131 | 0.66 | PLA2G2A (0.49) | HPGDMAPTTP53ALDH1A1CYP3A4 | |
| SCHEMBL9917139 | 0.66 | L3MBTL1 (0.48) | HPGDMAPTTP53ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2993215-B1 | Azabenzimidazo[2,1-a]benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2019-06-19 | — | — | EP | disclosed |