Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | VHL | P40337 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1881319 | 0.81 | KDM4E (0.60) | PKMKDM4ENAMPTSMN1; SMN2PREP | |
| SCHEMBL31268628 | 0.81 | PKM (0.51) | PKMKDM4ENAMPTSMN1; SMN2PREP | |
| SCHEMBL31391808 | 0.79 | KDM4E (0.62) | PKMKDM4ENAMPTSMN1; SMN2PREP | |
| SCHEMBL3372210 | 0.78 | PKM (0.60) | PKMKDM4ENAMPTSMN1; SMN2PREP | |
| SCHEMBL3048657 | 0.78 | SMN1; SMN2 (0.59) | PKMKDM4ENAMPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL15313327 | 0.77 | HDAC4 (0.41) | PKMKDM4ESMN1; SMN2NPC1HPGD | |
| SCHEMBL29242196 | 0.77 | PREP (0.46) | PKMKDM4ENAMPTSMN1; SMN2PREP | |
| SCHEMBL4559627 | 0.76 | SMN1; SMN2 (0.60) | KDM4ESMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL5277365 | 0.75 | PKM (0.56) | PKMKDM4ENAMPTSMN1; SMN2PREP | |
| SCHEMBL17971458 | 0.75 | NAMPT (0.49) | PKMKDM4ENAMPTNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115484938-A | Composition and use thereof | 博善人工智能剑桥有限公司 | 2022-12-16 | — | — | CN | disclosed |
| EP-2804859-B1 | NOVEL FAP INHIBITORS | UNIV ANTWERPEN (BE) | 2019-06-12 | — | — | EP | disclosed |