Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331063 | 0.87 | HPGDS (0.46) | MMP1MMP2MMP3HPGDSGRN | |
| SCHEMBL13735669 | 0.80 | MMP1 (0.47) | MMP1MMP2MMP3HPGDSGRN | |
| SCHEMBL13711061 | 0.80 | CTSK (0.42) | MMP1MMP2MMP3GRNSORT1 | |
| SCHEMBL3617417 | 0.80 | CTSK (0.42) | MMP1MMP2MMP3GRNSORT1 | |
| SCHEMBL13710937 | 0.80 | CTSK (0.42) | MMP1MMP2MMP3GRNSORT1 | |
| SCHEMBL15840387 | 0.78 | MMP1 (0.42) | MMP1MMP2MMP3HPGDSGRN | |
| SCHEMBL18435239 | 0.78 | CTSK (0.44) | MMP1MMP2MMP3CTSKCPB2 | |
| SCHEMBL13707910 | 0.78 | CTSK (0.44) | MMP1MMP2MMP3CTSKCPB2 | |
| SCHEMBL13707911 | 0.78 | CTSK (0.44) | MMP1MMP2MMP3CTSKCPB2 | |
| Trifluoroacetic Acid SCHEMBL4334895 | 0.78 | MMP1 (0.42) | MMP1MMP2MMP3HPGDSGRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019111225-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF NON‑ALCOHOLIC STEATOHEPATITIS | AVALIV THERAPEUTICS (US) | 2019-06-13 | — | — | WO | disclosed |