Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21101969 | 0.94 | ALDH1A1 (0.45) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL21102257 | 0.84 | ALDH1A1 (0.58) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL31304722 | 0.84 | HDAC1 (0.47) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL21101973 | 0.83 | HDAC1 (0.43) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL21102215 | 0.83 | HDAC1 (0.45) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL21102164 | 0.83 | MTNR1A (0.54) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL21102168 | 0.82 | HPGD (0.47) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL5168941 | 0.80 | ACHE (0.46) | ALDH1A1MAPK1POLBNPC1RAB9A | |
| SCHEMBL21102245 | 0.78 | ALDH1A1 (0.46) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL21101981 | 0.77 | ALDH1A1 (0.45) | HDAC1HDAC2HDAC3HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046736-B1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2019-06-12 | — | — | EP | disclosed |