Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.58 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 5/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30980094 | 0.90 | ALOX5 (0.61) | ALOX5GGPS1PTGES2PRKDCMGLL | |
| SCHEMBL283154 | 0.90 | ALOX5 (0.61) | ALOX5GGPS1PTGES2PRKDCMGLL | |
| SCHEMBL1687979 | 0.87 | ALOX5 (0.68) | ALOX5GGPS1PTGES2PRKDCATM | |
| SCHEMBL30120167 | 0.87 | ALOX5 (0.68) | ALOX5GGPS1PTGES2PRKDCATM | |
| SCHEMBL29427625 | 0.86 | ALOX5 (0.60) | ALOX5GGPS1PTGES2PRKDCMGLL | |
| SCHEMBL3862262 | 0.86 | ALOX5 (0.60) | ALOX5GGPS1PTGES2PRKDCMGLL | |
| SCHEMBL28594941 | 0.82 | ALOX5 (0.47) | ALOX5GGPS1PTGES2PRKDCMGLL | |
| SCHEMBL26272496 | 0.82 | ALOX5 (0.44) | ALOX5GGPS1PTGES2PRKDCMGLL | |
| SCHEMBL12996512 | 0.82 | ALOX5 (0.71) | ALOX5GGPS1PTGES2PRKDCATM | |
| SCHEMBL25586142 | 0.82 | ALOX5 (0.59) | ALOX5GGPS1PTGES2PRKDCMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200308129-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-10-01 | — | — | US | disclosed |
| WO-2019115577-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308129-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | DDC, CHRM5, AFF2 | ALOX5 2670/4885GGPS1 2850/4885PTGES2 4149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.