Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 8/20 | 1.00 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 1.00 |
| ▸ | PIM3 | Q86V86 | 1/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.75 |
| ▸ | HPGD | P15428 | 3/20 | 0.75 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | NAT1 | P18440 | 1/20 | 0.71 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.71 |
| ▸ | GSK3B | P49841 | 3/20 | 0.70 |
| ▸ | MAOA | P21397 | 3/20 | 0.70 |
| ▸ | MAOB | P27338 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1250387 | 1.00 | PIM1 (1.00) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL28303094 | 1.00 | PIM1 (1.00) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL2132747 | 1.00 | PIM1 (1.00) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL8188808 | 0.94 | PIM1 (0.89) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL8188811 | 0.94 | PIM1 (0.89) | PIM1PIM2PIM3AKR1B1HPGD | |
| Benzaldehyde SCHEMBL10480742 | 0.93 | PIM1 (0.86) | PIM1PIM2PIM3AKR1B1HPGD | |
| Benzaldehyde SCHEMBL10480890 | 0.93 | PIM1 (0.86) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL12891790 | 0.91 | PIM1 (0.83) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL1248780 | 0.91 | PIM1 (0.83) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL1248782 | 0.91 | PIM1 (0.83) | PIM1PIM2PIM3AKR1B1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 488 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890963-B | Benzylidene thiazolidinedione derivative, and preparation method and application thereof | 湖州师范学院 | 2023-05-05 | — | — | CN | claimed |
| CN-114890963-A | Benzylidene thiazolidinedione derivatives, and preparation method and application thereof | 湖州师范学院 | 2022-08-12 | — | — | CN | claimed |
| CN-112385019-A | Etchant composition | 朗姆研究公司 | 2021-02-19 | — | — | CN | claimed |
| US-20180202110-A1 | CHEMICAL COMPOSITION FOR ANTI-CORROSION MINERAL PAPER | CHENG KIT YEW NELSON (SG) | 2018-07-19 | — | — | US | claimed |
| EP-3329047-A1 | CHEMICAL COMPOSITION FOR ANTI-CORROSION MINERAL PAPER | Cheng Kit Yew, Nelson (SG) | 2018-06-06 | — | — | EP | claimed |
| US-9039925-B2 | Polishing slurry composition | UWIZ TECHNOLOGY CO., LTD. (TW) | 2015-05-26 | — | — | US | claimed |
| US-20130264515-A1 | POLISHING SLURRY COMPOSITION | UWIZ TECHNOLOGY CO., LTD. (TW) | 2013-10-10 | — | — | US | claimed |
| US-8501438-B2 | Production of glycoproteins with reduced O-glycosylation | GLYCOFI, INC. (US) | 2013-08-06 | — | — | US | claimed |
| US-20120237973-A1 | PRODUCTION OF GLYCOPROTEINS WITH REDUCED O-GLYCOSYLATION | GLYCOFI, INC. (US) | 2012-09-20 | — | — | US | claimed |
| US-8206949-B2 | Production of glycoproteins with reduced O-glycosylation | GLYCOFI, INC. (US) | 2012-06-26 | — | — | US | claimed |
| EP-1954815-A2 | PRODUCTION OF GLYCOPROTEINS WITH REDUCED O-GLYCOSYLATION | Glycofi, Inc. (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061631-A2 | PRODUCTION OF GLYCOPROTEINS WITH REDUCED O-GLYCOSYLATION | GLYCOFI, INC (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070071699-A1 | Benzylidene-1,3-thiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting their depigmentation and/or whitening | L'OREAL (FR) | 2007-03-29 | — | — | US | claimed |
| US-20070059260-A1 | Benzyl-1,3-thiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting their depigmentation and/or whitening | L'OREAL (FR) | 2007-03-15 | — | — | US | claimed |
| US-20070059265-A1 | Benzylidene-1,3-thiazolidine-2,4-dione compounds for stimulating or inducing the growth and/or for reducing the loss and/or for increasing the density of keratin fibers | L'OREAL (FR) | 2007-03-15 | — | — | US | claimed |
| EP-1738741-A2 | Use of benzylidene-1,3-thiazolidine-2,4-diones for favouring and/or inducing and/or stimulating the pigmentation of keratinic materials and/or for limiting their depigmentation and/or their bleaching | L'OREAL (FR) | 2007-01-03 | — | — | EP | claimed |
| EP-1739083-A1 | Benzylidene-1,3-thiazolidine-2,4-dione compounds, uses thereof and compositions for stimulating or inducing the growth and/or for reducing the loss and/or for increasing the density of keratin fibres | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| US-7091359-B2 | Process for the preparation of thiazolidinedione derivatives | SMITHKLINE BEECHAM PLC (GB) | 2006-08-15 | — | — | US | claimed |
| CN-1252065-A | Process for preparing substituted thiazolidinedione | SMITHKLINE BEECHAM PLC (GB) | 2000-05-03 | — | — | CN | claimed |
| EP-0343643-A2 | Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents | WARNER-LAMBERT COMPANY (US) | 1989-11-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070059260-A1 | Benzyl-1,3-thiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting their depigmentation and/or whitening | KRT18, TYR, MITF | PIM1 3552/4885PIM2 3593/4885PIM3 2964/4885 |
| US-20070059265-A1 | Benzylidene-1,3-thiazolidine-2,4-dione compounds for stimulating or inducing the growth and/or for reducing the loss and/or for increasing the density of keratin fibers | KRT18, FGF1, SMO | PIM1 3592/4885PIM2 3395/4885PIM3 3535/4885 |
| US-20130264515-A1 | POLISHING SLURRY COMPOSITION | H1-0, H1-2, SPTBN1 | PIM1 2641/4885PIM2 2562/4885PIM3 3246/4885 |
| US-20070071699-A1 | Benzylidene-1,3-thiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting their depigmentation and/or whitening | KRT18, TYR, MITF | PIM1 3707/4885PIM2 3458/4885PIM3 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.