Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 8/20 | 1.00 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 1.00 |
| ▸ | PIM3 | Q86V86 | 1/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.75 |
| ▸ | HPGD | P15428 | 3/20 | 0.75 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | NAT1 | P18440 | 1/20 | 0.71 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.71 |
| ▸ | GSK3B | P49841 | 3/20 | 0.70 |
| ▸ | MAOA | P21397 | 3/20 | 0.70 |
| ▸ | MAOB | P27338 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28303094 | 1.00 | PIM1 (1.00) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL2132747 | 1.00 | PIM1 (1.00) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL211085 | 1.00 | PIM1 (1.00) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL8188808 | 0.94 | PIM1 (0.89) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL8188811 | 0.94 | PIM1 (0.89) | PIM1PIM2PIM3AKR1B1HPGD | |
| Benzaldehyde SCHEMBL10480742 | 0.93 | PIM1 (0.86) | PIM1PIM2PIM3AKR1B1HPGD | |
| Benzaldehyde SCHEMBL10480890 | 0.93 | PIM1 (0.86) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL12891790 | 0.91 | PIM1 (0.83) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL1248780 | 0.91 | PIM1 (0.83) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL1248782 | 0.91 | PIM1 (0.83) | PIM1PIM2PIM3AKR1B1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1252065-A | Process for preparing substituted thiazolidinedione | SMITHKLINE BEECHAM PLC (GB) | 2000-05-03 | — | — | CN | claimed |
| JP-10101659-A | — | — | None | — | — | JP | disclosed |
| JP-11071358-A | — | — | None | — | — | JP | disclosed |
| JP-11049763-A | — | — | None | — | — | JP | disclosed |
| CN-122036586-A | Compositions and methods for modulating hair growth | 加利福尼亚大学董事会 | 2026-05-15 | — | — | CN | disclosed |
| US-20250304579-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-10-02 | — | — | US | disclosed |
| US-12227503-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-02-18 | — | — | US | disclosed |
| US-20250002919-A1 | REGENERATION OR REJUVENATION OF TISSUES AND ORGANS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-01-02 | — | — | US | disclosed |
| US-20240423964-A1 | METHODS AND COMPOSITIONS FOR IMPROVING NEUROMUSCULAR JUNCTION MORPHOLOGY AND FUNCTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2024-12-26 | — | — | US | disclosed |
| EP-4419658-A1 | METHODS AND COMPOSITIONS FOR IMPROVING NEUROMUSCULAR JUNCTION MORPHOLOGY AND FUNCTION | The Board of Trustees of the Leland Stanford Junior University (US) | 2024-08-28 | — | — | EP | disclosed |
| EP-0332331-B1 | Thiazolidinedione hypoglycemic agents | PFIZER (US) | 1994-02-09 | — | — | EP | disclosed |
| US-5246948-A | Antiinflammatory, antipyretic, analgesic, antiallergic, immunosupressing or immunomodulating activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0555249-A1 | THIAZOLIDINEDIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | disclosed |
| US-5223522-A | Anticholesterol agents | PFIZER INC. (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0522606-A2 | Pyridine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-13 | — | — | EP | disclosed |
| US-5120754-A | Anticholesterol and antidiabetic agents | PFIZER INC. (US) | 1992-06-09 | — | — | US | disclosed |
| WO-1992007839-A1 | THIAZOLIDINEDIONE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | disclosed |
| US-5061717-A | ANTICHOLESTEROL AGENTS | PFIZER INC. (US) | 1991-10-29 | — | — | US | disclosed |
| EP-0389699-A1 | Thiazolidinedione derivatives as hypoglycemic agents | PFIZER INC. (US) | 1990-10-03 | — | — | EP | disclosed |
| EP-0332331-A2 | Thiazolidinedione hypoglycemic agents | PFIZER INC. (US) | 1989-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304579-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | PIM1 3827/4885PIM2 4103/4885PIM3 3637/4885 |
| US-12227503-B2 | Compositions and methods for modulating hair growth | PC, FH, SLC25A1 | PIM1 3827/4885PIM2 4103/4885PIM3 3637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.