Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14606394 | 0.79 | — | — | |
| SCHEMBL16273431 | 0.78 | PLG (0.37) | EPHX2 | |
| SCHEMBL20468728 | 0.78 | EPHX1 (0.33) | — | |
| SCHEMBL16887696 | 0.77 | SHBG (0.41) | EPHX2TSHRSHBG | |
| SCHEMBL14747461 | 0.77 | CES2 (0.50) | TSHR | |
| SCHEMBL16887508 | 0.77 | SHBG (0.41) | EPHX2TSHRSHBG | |
| SCHEMBL10277235 | 0.77 | SHBG (0.41) | EPHX2TSHRSHBG | |
| SCHEMBL10437811 | 0.75 | EPHX2 (0.36) | EPHX2TSHRSHBG | |
| SCHEMBL32661372 | 0.75 | NLRP3 (0.41) | EPHX2TSHRSHBG | |
| SCHEMBL10437912 | 0.75 | EPHX2 (0.36) | EPHX2TSHRSHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019135010-A1 | TIACUMICIN DERIVATIVES AND THEIR USE AS ANTIBIOTICS | Universität Zürich (CH) | 2019-07-11 | — | — | WO | disclosed |
| EP-3508492-A1 | TIACUMICIN DERIVATIVES AND THEIR USE AS ANTIBIOTICS | Universität Zürich (CH) | 2019-07-10 | — | — | EP | disclosed |