Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 16/20 | 0.34 |
| ▸ | MAOA | P21397 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15870032 | 0.86 | LMNA (0.40) | MAOBMAOALMNABCHE | |
| SCHEMBL26831741 | 0.86 | LMNA (0.40) | MAOBMAOALMNABCHE | |
| SCHEMBL24247404 | 0.86 | LMNA (0.40) | MAOBMAOALMNABCHE | |
| SCHEMBL1769287 | 0.86 | — | — | |
| SCHEMBL2475455 | 0.75 | — | — | |
| SCHEMBL5010160 | 0.75 | — | — | |
| SCHEMBL123292 | 0.75 | — | — | |
| SCHEMBL3230975 | 0.74 | ALDH1A1 (0.40) | GNAI3GNAO1GNAI1LMNA | |
| SCHEMBL1206778 | 0.74 | MAOB (0.40) | MAOBMAOABCHE | |
| SCHEMBL25800786 | 0.74 | ALDH1A1 (0.40) | MAOBMAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019135010-A1 | TIACUMICIN DERIVATIVES AND THEIR USE AS ANTIBIOTICS | Universität Zürich (CH) | 2019-07-11 | — | — | WO | disclosed |
| EP-3508492-A1 | TIACUMICIN DERIVATIVES AND THEIR USE AS ANTIBIOTICS | Universität Zürich (CH) | 2019-07-10 | — | — | EP | disclosed |
| EP-3508492-A1 | TIACUMICIN DERIVATIVES AND THEIR USE AS ANTIBIOTICS | Universität Zürich (CH) | 2019-07-10 | — | — | EP | disclosed |