SCHEMBL1769287

SCHEMBL1769287

C#CCN1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24247404 1.00 LMNA (0.40)
SCHEMBL26831741 1.00 LMNA (0.40)
SCHEMBL15870032 1.00 LMNA (0.40)
SCHEMBL5010160 0.87
SCHEMBL123292 0.87
SCHEMBL2475455 0.87
SCHEMBL1206778 0.86 MAOB (0.40)
SCHEMBL21111085 0.86 GNAI3 (0.35)
SCHEMBL25800786 0.86 ALDH1A1 (0.40)
SCHEMBL633237 0.86 NPSR1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3749670-B1 5-ALKYLTHIO-7-[(4-ARYLBENZYL)AMINO]-1(2)H-PYRAZOLO[4,3-D]PYRIMIDINES FOR TREATMENT OF LYMPHOMA UNIV PALACKEHO (CZ) 2021-10-06 EP claimed
EP-2625217-B1 CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS NOVARTIS AG (CH) 2018-07-04 EP claimed
EP-2625218-B1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2018-04-25 EP claimed
EP-2598937-B1 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2016-06-29 EP claimed
EP-2499201-B1 POLYMERIC COMPOSITIONS AND METHOD OF MAKING AND ARTICLES THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2017-05-10 EP disclosed
US-20160369069-A1 POLYMERIC COMPOSITIONS AND METHOD OF MAKING AND ARTICLES THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2016-12-22 US disclosed
CN-102597120-B Polymer compositions, methods of making, and articles 3M INNOVATIVE PROPERTIES CO 2015-05-27 CN disclosed
US-20140187722-A1 POLYMERIC COMPOSITIONS AND METHOD OF MAKING AND ARTICLES THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-07-03 US disclosed
US-8703877-B2 Polymeric compositions and method of making and articles thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-04-22 US disclosed
EP-2499201-A2 POLYMERIC COMPOSITIONS AND METHOD OF MAKING AND ARTICLES THEREOF 3M Innovative Properties Company (US) 2012-09-19 EP disclosed
WO-2011059994-A2 POLYMERIC COMPOSITIONS AND METHOD OF MAKING AND ARTICLES THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-05-19 WO disclosed
US-20110112254-A1 POLYMERIC COMPOSITIONS AND METHOD OF MAKING AND ARTICLES THEREOF 3M INNOVATIVE PROPERTIES COMPANY 2011-05-12 US disclosed