Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179828 | 0.91 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3SSTR4 | |
| SCHEMBL21191249 | 0.91 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3SSTR4 | |
| SCHEMBL30785730 | 0.91 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3SSTR4 | |
| Trifluoroacetic Acid SCHEMBL28488935 | 0.83 | SSTR4 (0.32) | SSTR4 | |
| Trifluoroacetic Acid SCHEMBL31470239 | 0.81 | SSTR4 (0.31) | SSTR4 | |
| SCHEMBL21111241 | 0.78 | — | — | |
| SCHEMBL22329077 | 0.78 | SSTR4 (0.30) | SSTR4 | |
| SCHEMBL5963180 | 0.76 | SLC6A2 (0.34) | SLC6A2SLC6A4SSTR4 | |
| SCHEMBL20524428 | 0.73 | TSHR (0.31) | — | |
| Trifluoroacetic Acid SCHEMBL2268475 | 0.72 | SSTR4 (0.36) | SLC6A2SLC6A3SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3766880-B1 | SOLID FORM OF DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) | 2023-07-26 | — | — | EP | disclosed |
| US-11434235-B2 | Solid form of dihydropyrimidine compound and preparation method therefor and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2022-09-06 | — | — | US | disclosed |
| US-11166954-B2 | Dihydropyrimidine compound and preparation method and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2021-11-09 | — | — | US | disclosed |
| EP-3508483-B1 | DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) | 2021-10-06 | — | — | EP | disclosed |
| US-20210024514-A1 | SOLID FORM OF DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2021-01-28 | — | — | US | disclosed |
| EP-3766880-A1 | SOLID FORM OF DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2021-01-20 | — | — | EP | disclosed |
| US-20200253971-A1 | DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-08-13 | — | — | US | disclosed |
| US-10696669-B2 | Dihydropyrimidine compound and preparation method and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICALS CO., LTD. (CN) | 2020-06-30 | — | — | US | disclosed |
| US-20190225603-A1 | DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2019-07-25 | — | — | US | disclosed |
| EP-3508483-A1 | DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2019-07-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11166954-B2 | Dihydropyrimidine compound and preparation method and use thereof | DPYD, DHPS, HPRT1 | SLC6A2 3400/4885SLC6A4 2966/4885SLC6A3 3611/4885 |
| US-20190225603-A1 | DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | DPYD, TYMP, DHPS | SLC6A2 3808/4885SLC6A4 3097/4885SLC6A3 3688/4885 |
| US-20210024514-A1 | SOLID FORM OF DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | DPYD, DHFR, FDPS | SLC6A2 3217/4885SLC6A4 1131/4885SLC6A3 2616/4885 |
| US-20200253971-A1 | DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | DPYD, DHPS, HPRT1 | SLC6A2 3400/4885SLC6A4 2966/4885SLC6A3 3611/4885 |
| US-11434235-B2 | Solid form of dihydropyrimidine compound and preparation method therefor and use thereof | DPYD, DHFR, FDPS | SLC6A2 3217/4885SLC6A4 1131/4885SLC6A3 2616/4885 |
| US-10696669-B2 | Dihydropyrimidine compound and preparation method and use thereof | DPYD, TYMP, DHPS | SLC6A2 3808/4885SLC6A4 3097/4885SLC6A3 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.