SCHEMBL21112841

SCHEMBL21112841

CO[SiH](Oc1ccccc1)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.42
LTA4H P09960 2/20 0.37
RIPK1 Q13546 1/20 0.36
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.33
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KCNA3 P22001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705501 0.89 CA4 (0.42) CA4LTA4HRIPK1TSHRMAPK1
SCHEMBL19927127 0.78 LTA4H (0.38) CA4LTA4HRIPK1TSHRMAPK1
SCHEMBL28647701 0.77 CA4 (0.34) CA4LTA4HRIPK1ATML3MBTL1
Benzene SCHEMBL27799664 0.75
SCHEMBL18417862 0.75 CA4 (0.42) CA4LTA4HRIPK1TSHRMAPK1
SCHEMBL18417864 0.73 CA4 (0.40) CA4LTA4HRIPK1TSHRMAPK1
SCHEMBL7058914 0.72 CA4 (0.50) CA4LTA4HTSHRKCNA3
SCHEMBL2115686 0.72 CA4 (0.50) CA4LTA4HTSHRKCNA3
SCHEMBL18426396 0.71 CA4 (0.39) CA4LTA4HRIPK1TSHRMAPK1
SCHEMBL1051361 0.70 LTA4H (0.39) CA4LTA4HTSHRALDH1A1KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507104-B1 PRODUCTION OF CIS-1,4-POLYDIENES WITH MULTIPLE SILANE FUNCTIONAL GROUPS PREPARED BYIN-SITU BRIDGESTONE CORP (JP) 2024-03-27 EP disclosed
CN-109641482-B Preparation of cis-1, 4-polydienes having multiple silane functional groups prepared by in situ hydrosilylation of polymer glues 株式会社普利司通 2021-11-05 CN disclosed
US-10975178-B2 Production of cis-1,4-polydienes with multiple silane functional groups prepared by in-situ hydrosilylation of polymer cement BRIDGESTONE CORPORATION (JP) 2021-04-13 US disclosed
US-20190211120-A1 Production Of Cis-1,4-Polydienes With Multiple Silane Functional Groups Prepared By In-Situ Hydrosilylation Of Polymer Cement BRIDGESTONE CORPORATION (JP) 2019-07-11 US disclosed