Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994246 | 0.82 | KDM4E (0.38) | KDM4ECYP1A2CYP2C9CYP2C19ATM | |
| SCHEMBL19994247 | 0.81 | CYP3A4 (0.43) | KDM4ECYP1A2CYP2C9CYP2C19SLC6A4 | |
| SCHEMBL21113813 | 0.79 | SLC6A2 (0.30) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL20000648 | 0.78 | AR (0.46) | KDM4ESLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL18529474 | 0.77 | KDM4E (0.35) | KDM4ECYP1A2CYP2C9CYP2C19ATM | |
| SCHEMBL29240602 | 0.73 | MAOB (0.37) | SLC6A4ALDH1A1HTR2AKCNH2 | |
| SCHEMBL19994257 | 0.71 | CYP3A4 (0.34) | KDM4ECYP1A2CYP2C9CYP2C19SLC6A4 | |
| SCHEMBL10815927 | 0.70 | POLB (0.36) | CYP1A2CYP2C19 | |
| SCHEMBL20641013 | 0.69 | THRB (0.36) | KDM4ECYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL21113821 | 0.69 | KDM4E (0.31) | KDM4ELIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190211002-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190211002-A1 | NOVEL TRIAZOLE DERIVATIVES | ERG28, CYP51A1, SBK3 | KDM4E 2612/4885CYP1A2 467/4885CYP2C9 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.