SCHEMBL21114663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21114657	0.87	CTSD (0.43)	MAPTL3MBTL1LMNAMAPK1MEN1
	SCHEMBL21114652	0.85	HCRTR1 (0.50)	HCRTR1MAPTL3MBTL1LMNAGAA
	SCHEMBL21114592	0.84	IRAK4 (0.47)	HCRTR1TDP1LMNAKDM4EALDH1A1
	SCHEMBL21114581	0.82	HCRTR1 (0.47)	HCRTR1MAPTL3MBTL1LMNAGAA
	SCHEMBL21114618	0.81	ALDH1A1 (0.46)	POLBTDP1MAPTLMNAMAPK1
	SCHEMBL20981421	0.78	HCRTR1 (0.54)	HCRTR1MAPTL3MBTL1LMNAGAA
	SCHEMBL21114621	0.78	HCRTR1 (0.43)	HCRTR1MAPTL3MBTL1LMNAGAA
	SCHEMBL23781755	0.74	HCRTR1 (0.50)	HCRTR1POLBTDP1MAPTL3MBTL1
	SCHEMBL21114671	0.74	HCRTR1 (0.53)	HCRTR1MAPTL3MBTL1LMNAGAA
	SCHEMBL10426439	0.74	HCRTR1 (0.53)	HCRTR1MAPTL3MBTL1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.