SCHEMBL21114592

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21114657	0.86	CTSD (0.43)	ALDH1A1LMNA
	SCHEMBL21114663	0.84	HCRTR1 (0.45)	KCNK3KCNK9ALDH1A1KDM4ELMNA
	SCHEMBL21114690	0.81	PRSS1 (0.36)	ALDH1A1KDM4ELMNA
	SCHEMBL21114681	0.79	IRAK4 (0.48)	IRAK4IDO1TDO2KCNK3KCNK9
	SCHEMBL20981405	0.77	IRAK4 (0.58)	IRAK4IDO1TDO2KCNK3KCNK9
	SCHEMBL21114618	0.76	ALDH1A1 (0.46)	ALDH1A1KDM4ELMNATDP1
	SCHEMBL21114590	0.73	IRAK4 (0.57)	IRAK4IDO1TDO2KCNK3KCNK9
	SCHEMBL21114562	0.72	IRAK4 (0.53)	IRAK4IDO1TDO2KCNK3KCNK9
	SCHEMBL3261086	0.72	IRAK4 (0.59)	IRAK4IDO1TDO2KCNK3KCNK9
	SCHEMBL28293902	0.70	IRAK4 (0.70)	IRAK4IDO1TDO2KCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.