Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6121689 | 0.85 | TSHR (0.41) | ALDH1A1POLBL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL6123149 | 0.82 | ALDH1A1 (0.48) | ALDH1A1POLBTSHRSMN1; SMN2GAA | |
| SCHEMBL15238847 | 0.80 | ALDH1A1 (0.51) | ALDH1A1POLBTSHRSMN1; SMN2GAA | |
| SCHEMBL17397586 | 0.80 | ALDH1A1 (0.51) | ALDH1A1POLBTSHRSMN1; SMN2GAA | |
| SCHEMBL21114756 | 0.79 | TSHR (0.45) | ALDH1A1POLBL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL21114755 | 0.79 | TSHR (0.45) | ALDH1A1POLBL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL6121955 | 0.79 | CTSK (0.48) | ALDH1A1POLBL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL6122933 | 0.79 | CTSK (0.48) | ALDH1A1POLBL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL6121705 | 0.77 | ALDH1A1 (0.38) | ALDH1A1POLBL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL6123293 | 0.76 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1SMN1; SMN2NPC1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640721-A2 | AGONISTS THAT ENHANCE BINDING OF INTEGRIN-EXPRESSING CELLS TO INTEGRIN RECEPTORS | Texas Heart Institute (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012068251-A2 | AGONISTS THAT ENHANCE BINDING OF INTEGRIN-EXPRESSING CELLS TO INTEGRIN RECEPTORS | TEXAS HEART INSTITUTE (US) | 2012-05-24 | — | — | WO | disclosed |