SCHEMBL21114780

SCHEMBL21114780

CCCCCCCCCCCCCCC1=CC(=O)N(C(C)CCCCCCCC)C1=O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.41
BACE1 P56817 1/20 0.41
PTPN1 P18031 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
PTGS2 P35354 8/20 0.37
ALOX5 P09917 5/20 0.37
GLS2 Q9UI32 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CYP2C19 P33261 1/20 0.36
PKM P14618 1/20 0.36
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MGLL Q99685 3/20 0.35
FAAH O00519 2/20 0.35
PTGS1 P23219 3/20 0.34
SHMT2 P34897 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20862873 0.81 ACHE (0.44) ACHEBACE1PTPN1PTGS2ALOX5
SCHEMBL23811151 0.81 SMN1; SMN2 (0.41) PTPN1SMN1; SMN2LMNAPTGS2ALDH1A1
SCHEMBL25532173 0.78 SMN1; SMN2 (0.38) PTPN1SMN1; SMN2LMNAPTGS2ALDH1A1
SCHEMBL3482625 0.75 MGLL (0.50) SMN1; SMN2LMNAPTGS2ALDH1A1CYP2C19
SCHEMBL4005408 0.74 ACHE (0.49) ACHEBACE1PTPN1PTGS2ALOX5
SCHEMBL3482787 0.73 MGLL (0.47) SMN1; SMN2LMNAPTGS2ALDH1A1CYP2C19
SCHEMBL357101 0.72 ACHE (0.47) ACHEBACE1PTPN1LMNAPTGS2
SCHEMBL28098556 0.72 ACHE (0.47) ACHEBACE1PTPN1PTGS2ALOX5
SCHEMBL28098404 0.72 ACHE (0.47) ACHEBACE1PTPN1PTGS2ALOX5
SCHEMBL1535467 0.72 ACHE (0.47) ACHEBACE1PTPN1PTGS2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115210271-B N-substituted maleimide polymer and process for producing the same 株式会社日本触媒 2023-08-25 CN disclosed
US-10982167-B2 Viscosity index improver and lubricating oil composition NIPPON SHOKUBAI CO., LTD. (JP) 2021-04-20 US disclosed
US-20190211281-A1 VISCOSITY INDEX IMPROVER AND LUBRICATING OIL COMPOSITION NIPPON SHOKUBAI CO., LTD. (JP) 2019-07-11 US disclosed