Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21114780 | 0.81 | ACHE (0.41) | SMN1; SMN2LMNAPKMHTTHSD17B10 | |
| SCHEMBL14493752 | 0.79 | POLB (0.32) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL6937953 | 0.79 | GPR84 (0.40) | SMN1; SMN2LMNAHSD17B10ALDH1A1POLB | |
| SCHEMBL3482625 | 0.78 | MGLL (0.50) | SMN1; SMN2LMNAPKMHTTHSD17B10 | |
| SCHEMBL3482787 | 0.75 | MGLL (0.47) | SMN1; SMN2LMNAPKMHTTHSD17B10 | |
| SCHEMBL14493740 | 0.74 | TSHR (0.32) | — | |
| SCHEMBL29257418 | 0.72 | TDP1 (0.54) | LMNAALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL30423475 | 0.72 | TDP1 (0.54) | LMNAALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL6941606 | 0.72 | PTPN1 (0.41) | HSD17B10ALDH1A1POLBPTPN1 | |
| SCHEMBL18504935 | 0.71 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAPKMHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210285955-A1 | METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES | WARP DRIVE BIO, INC. | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210285955-A1 | METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES | FKBP8, PIN1, FKBP1A | SMN1; SMN2 4204/4885LMNA 3566/4885PKM 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.