Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 14/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.76 |
| ▸ | TSHR | P16473 | 3/20 | 0.76 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.76 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | GMNN | O75496 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.76 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.76 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.76 |
| ▸ | HTR1A | P08908 | 1/20 | 0.76 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686686 | 1.00 | ADCY1 (0.76) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| SCHEMBL10688101 | 0.87 | ADCY1 (0.71) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| Colforsin SCHEMBL1517319 | 0.86 | ADCY1 (1.00) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| Colforsin SCHEMBL21530309 | 0.86 | ADCY1 (1.00) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| Colforsin SCHEMBL4928 | 0.86 | ADCY1 (1.00) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| Colforsin SCHEMBL23750589 | 0.86 | ADCY1 (1.00) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| Colforsin SCHEMBL16342714 | 0.86 | ADCY1 (1.00) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| Colforsin SCHEMBL4917705 | 0.86 | ADCY1 (1.00) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| Colforsin SCHEMBL14614874 | 0.86 | ADCY1 (1.00) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| Colforsin SCHEMBL10409866 | 0.86 | ADCY1 (1.00) | ADCY1MAPK1CYP3A4TSHRSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194706-A1 | Biosynthesis of Oxidised 13R-MO and Related Compounds | UNIVERSITY OF COPENHAGEN (DK) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194706-A1 | Biosynthesis of Oxidised 13R-MO and Related Compounds | CYP11B1, CYP2A13, CYP4Z1 | ADCY1 199/4885MAPK1 2732/4885CYP3A4 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.