Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 12/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18535562 | 0.85 | MEN1 (0.57) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL23316808 | 0.80 | ESR2 (0.76) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL21116158 | 0.77 | MIF (0.54) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL22625522 | 0.75 | MIF (0.67) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL18535548 | 0.74 | ESR2 (0.49) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL24595591 | 0.72 | ESR2 (0.49) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL18535593 | 0.72 | MEN1 (0.47) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL220708 | 0.72 | HSD17B3 (0.65) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL30405545 | 0.72 | HSD17B3 (0.65) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL21761391 | 0.71 | ESR2 (0.51) | MEN1KMT2AGLAESR2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502147-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |