Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 10/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18535562 | 0.86 | MEN1 (0.57) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL18535466 | 0.82 | GPR55 (0.44) | GLACA12CA1CA9NPC1 | |
| SCHEMBL23713466 | 0.81 | CA12 (0.48) | GLACA12CA1CA9POLB | |
| SCHEMBL23713467 | 0.79 | CA12 (0.35) | MEN1KMT2AGLACA12CA1 | |
| SCHEMBL18535548 | 0.75 | ESR2 (0.49) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL23683806 | 0.72 | ESR1 (0.47) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL23316808 | 0.72 | ESR2 (0.76) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL21735206 | 0.72 | ALOX5 (0.47) | MEN1KMT2APTGS1ERAP1KDM4E | |
| SCHEMBL21116073 | 0.72 | MEN1 (0.53) | MEN1KMT2AGLAESR2MIF | |
| SCHEMBL21116525 | 0.70 | ESR1 (0.46) | MEN1KMT2AGLAESR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4327779-A2 | SYSTEM AND METHOD | AMO Ireland (IE) | 2024-02-28 | — | — | EP | disclosed |
| EP-3958788-B1 | SYSTEM AND METHOD | AMO Ireland (IE) | 2023-11-22 | — | — | EP | disclosed |
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | disclosed |
| US-20210363122-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-11-25 | — | — | US | disclosed |
| US-11078177-B2 | Compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-08-03 | — | — | US | disclosed |
| US-10457658-B2 | Compounds for optically active devices | MERCK PATENT GMBH (DE) | 2019-10-29 | — | — | US | disclosed |
| WO-2017032442-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2017-03-02 | — | — | WO | disclosed |
| EP-3133065-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363122-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | PDE6C, ALDH1A2, PDE6A | MEN1 2466/4885KMT2A 4409/4885GLA 315/4885 |
| US-10457658-B2 | Compounds for optically active devices | PDE6C, ALDH1A2, PDE6A | MEN1 2466/4885KMT2A 4409/4885GLA 315/4885 |
| US-11078177-B2 | Compounds for optically active devices | PDE6C, ALDH1A2, PDE6A | MEN1 2466/4885KMT2A 4409/4885GLA 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.