Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.51 |
| ▸ | MIF | P14174 | 12/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22590866 | 0.86 | HSD17B3 (0.57) | ESR2MIFMEN1RAB9AKMT2A | |
| SCHEMBL18583399 | 0.84 | MAOB (0.57) | MIFMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL18535562 | 0.83 | MEN1 (0.57) | ESR2MIFMEN1RAB9AKMT2A | |
| SCHEMBL23713550 | 0.80 | MAOB (0.45) | MEN1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL22625522 | 0.80 | MIF (0.67) | ESR2MIFMEN1RAB9AKMT2A | |
| SCHEMBL18583371 | 0.77 | KDM4E (0.46) | MEN1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL18535548 | 0.77 | ESR2 (0.49) | ESR2MIFMEN1RAB9AKMT2A | |
| SCHEMBL21761390 | 0.76 | MIF (0.62) | ESR2MIFMEN1RAB9AKMT2A | |
| SCHEMBL21116158 | 0.75 | MIF (0.54) | ESR2MIFMEN1RAB9AKMT2A | |
| SCHEMBL220708 | 0.74 | HSD17B3 (0.65) | ESR2MIFMEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3958788-B1 | SYSTEM AND METHOD | AMO Ireland (IE) | 2023-11-22 | — | — | EP | disclosed |
| US-11702396-B2 | Hydrophobic compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702396-B2 | Hydrophobic compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11001576-B2 | Compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| EP-3583102-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| EP-3583101-B1 | BIS-COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-10-28 | — | — | EP | disclosed |
| US-20200062739-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702396-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | ESR2 3189/4885MIF 951/4885MEN1 3033/4885 |
| US-20200062739-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | PDE6C, PDE6A, PDE6D | ESR2 3107/4885MIF 2239/4885MEN1 1816/4885 |
| US-11001576-B2 | Compounds for optically active devices | PDE6C, PDE6A, PDE6D | ESR2 3107/4885MIF 2239/4885MEN1 1816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.