SCHEMBL21116336

SCHEMBL21116336

Cc1cccc(-c2ccc3c4ccccc4n(-c4cc(-c5ccc(C#N)c(-n6c7ccccc7c7ccc(-c8cccc(C)c8)cc76)c5)ccc4C#N)c3c2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.47
IMPDH2 P12268 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
MAPK1 P28482 2/20 0.36
LMNA P02545 1/20 0.36
KDM4E B2RXH2 2/20 0.36
F2 P00734 1/20 0.36
PLAU P00749 1/20 0.36
ELANE P08246 1/20 0.36
CTRB1 P17538 1/20 0.36
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HIF1A Q16665 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
KDM4A O75164 1/20 0.35
KDM5B Q9UGL1 1/20 0.35
S1PR4 O95977 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21116334 0.93 AR (0.47) ARIMPDH2SMN1; SMN2ALDH1A1HPGD
SCHEMBL21116544 0.91 AR (0.38) ARIMPDH2SMN1; SMN2ALDH1A1LMNA
SCHEMBL21116543 0.91 AR (0.38) ARIMPDH2SMN1; SMN2ALDH1A1LMNA
SCHEMBL20150302 0.90 AR (0.40) ARIMPDH2SMN1; SMN2ALDH1A1HPGD
SCHEMBL21116457 0.88 ALDH1A1 (0.40) IMPDH2SMN1; SMN2ALDH1A1HPGDMAPK1
SCHEMBL21116333 0.87 AR (0.51) ARIMPDH2KDM4EMAPTL3MBTL1
SCHEMBL21131800 0.87 AR (0.44) ARIMPDH2SMN1; SMN2ALDH1A1HPGD
SCHEMBL23798858 0.86 AR (0.38) ARIMPDH2SMN1; SMN2ALDH1A1HPGD
SCHEMBL21116459 0.86 AR (0.38) ARIMPDH2SMN1; SMN2ALDH1A1HPGD
SCHEMBL21116545 0.86 AR (0.38) ARIMPDH2SMN1; SMN2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136294-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2021-10-05 US disclosed
EP-3478656-B1 DICARBAZOLE DIPHENYL DERIVATIVES FOR USE IN OPTOPELECTRONIC DEVICES CYNORA GMBH (DE) 2021-09-08 EP disclosed
US-20190194130-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194130-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, NOX3, ORC3 AR 1096/4885IMPDH2 4294/4885SMN1; SMN2 3470/4885
US-11136294-B2 Organic molecules for use in optoelectronic devices OR10J3, ORC3, NOX3 AR 1080/4885IMPDH2 4355/4885SMN1; SMN2 3412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.