SCHEMBL21116708

SCHEMBL21116708

c1ccc(-n2c3ccccc3c3cc(-n4c5ccccc5c5c6sc7c(ccc8c7c7ccccc7n8-c7ccc8c(c7)c7ccccc7n8-c7ccccc7)c6ccc54)ccc32)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.51
KDM4E B2RXH2 1/20 0.51
ATM Q13315 1/20 0.51
JAK2 O60674 1/20 0.36
JAK3 P52333 1/20 0.36
KMT2A Q03164 3/20 0.33
HSD17B10 Q99714 2/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
BRCA1 P38398 1/20 0.33
RAC2 P15153 1/20 0.33
RAC3 P60763 1/20 0.33
CDC42 P60953 1/20 0.33
RAC1 P63000 1/20 0.33
PTPN1 P18031 2/20 0.33
HDAC4 P56524 1/20 0.32
MAPK8 P45983 2/20 0.32
IL1R1 P14778 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17108975 1.00 L3MBTL1 (0.51) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL16484493 0.97 L3MBTL1 (0.49) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL21116690 0.94 L3MBTL1 (0.51) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL17108979 0.93 L3MBTL1 (0.53) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL17246538 0.92 ATM (0.46) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL16283085 0.92 ATM (0.46) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL21116691 0.91 KDM4E (0.52) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL11932984 0.91 L3MBTL1 (0.57) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL16484994 0.90 KDM4E (0.39) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL17109032 0.90 KDM4E (0.47) L3MBTL1KDM4EATMJAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190194219-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194219-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH SAME OR10J3, EML4, AOC2 L3MBTL1 2990/4885KDM4E 2872/4885ATM 2194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.