SCHEMBL21116952

SCHEMBL21116952

c1ccc(-n2c3ccccc3c3c2ccc2c4ccc5c(c6ccccc6n5-c5ccccc5)c4n(-c4ccccc4)c23)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
ATM Q13315 1/20 0.61
JAK2 O60674 1/20 0.39
JAK3 P52333 1/20 0.39
MAPK1 P28482 1/20 0.38
KMT2A Q03164 4/20 0.38
MAPK8 P45983 2/20 0.38
IL1R1 P14778 1/20 0.38
ALDH1A1 P00352 3/20 0.38
CYP1A2 P05177 1/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
CYP2C19 P33261 1/20 0.38
PGR P06401 2/20 0.38
MEN1 O00255 3/20 0.37
MAPK9 P45984 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4378079 0.95 L3MBTL1 (0.64) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL30092608 0.95 L3MBTL1 (0.64) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL19383003 0.93 KDM4E (0.53) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL10027641 0.93 L3MBTL1 (0.62) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL31744513 0.93 L3MBTL1 (0.62) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL26060236 0.93 L3MBTL1 (0.62) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL12691126 0.93 L3MBTL1 (0.62) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL10027526 0.93 L3MBTL1 (0.62) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL17245455 0.93 L3MBTL1 (0.62) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL16484322 0.92 KDM4E (0.56) KDM4EL3MBTL1ATMJAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024135588-A1 PHOTOELECTRIC CONVERSION ELEMENT CONTAINING PHOTOELECTRIC CONVERSION ELEMENT MATERIAL 日鉄ケミカル&マテリアル株式会社 2024-06-27 WO disclosed
US-20190194219-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194219-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH SAME OR10J3, EML4, AOC2 KDM4E 2872/4885L3MBTL1 2990/4885ATM 2194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.