Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.34 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 3/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980988 | 0.84 | THRB (0.43) | THRBTSHRHPGDPTGER4ALDH1A1 | |
| SCHEMBL22648161 | 0.76 | MAPT (0.48) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL21117538 | 0.75 | BTK (0.37) | THRBTSHRHPGDPTGER4ALDH1A1 | |
| SCHEMBL23409891 | 0.73 | TSHR (0.44) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL27214690 | 0.73 | THRB (0.48) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL20202290 | 0.73 | THRB (0.41) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL988048 | 0.72 | THRB (0.57) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL22648042 | 0.72 | SMN1; SMN2 (0.45) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL24439640 | 0.72 | THRB (0.40) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL28744595 | 0.72 | THRB (0.38) | THRBTSHRHPGDPTGER4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008096-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2019-06-26 | — | — | EP | disclosed |