Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22648161 | 0.84 | MAPT (0.48) | THRBALDH1A1MAPTTSHRHPGD | |
| SCHEMBL3210606 | 0.82 | ALDH1A1 (0.44) | THRBALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL23409891 | 0.81 | TSHR (0.44) | THRBALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL988048 | 0.80 | THRB (0.57) | THRBALDH1A1MAPTLMNATSHR | |
| SCHEMBL22648042 | 0.80 | SMN1; SMN2 (0.45) | THRBALDH1A1LMNATSHRHPGD | |
| SCHEMBL23463871 | 0.79 | THRB (0.56) | THRBALDH1A1LMNATSHRHPGD | |
| SCHEMBL17350743 | 0.79 | SMN1; SMN2 (0.40) | THRBALDH1A1MAPTKDM4ERCE1 | |
| SCHEMBL7633786 | 0.78 | THRB (0.51) | THRBALDH1A1MAPTTSHRHPGD | |
| SCHEMBL7592166 | 0.78 | THRB (0.43) | THRBALDH1A1MAPTKDM4ETSHR | |
| SCHEMBL2721790 | 0.77 | THRB (0.65) | THRBALDH1A1MAPTKDM4ERCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022104137-A1 | SUBSTITUTED PROPANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS | FACEBOOK TECHNOLOGIES, LLC (US) | 2022-05-19 | — | — | WO | disclosed |