Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981015 | 0.84 | PTGER4 (0.48) | TP53HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL21117560 | 0.84 | THRB (0.36) | THRBTP53HDAC1HDAC2MAPT | |
| SCHEMBL18633372 | 0.82 | THRB (0.37) | THRBHDAC1HDAC3HDAC2MAPT | |
| SCHEMBL23463871 | 0.71 | THRB (0.56) | THRBTP53HPGDTSHRALDH1A1 | |
| SCHEMBL23409891 | 0.71 | TSHR (0.44) | THRBTP53MAPTKMT2AHPGD | |
| SCHEMBL22648161 | 0.70 | MAPT (0.48) | THRBTP53MAPTKMT2AHPGD | |
| SCHEMBL28250427 | 0.70 | THRB (0.45) | THRBTP53MAPTHPGDTSHR | |
| SCHEMBL27214690 | 0.68 | THRB (0.48) | THRBTP53HDAC1HDAC3HDAC2 | |
| SCHEMBL19980955 | 0.67 | HDAC1 (0.38) | HDAC1HDAC3HDAC2MAPTHPGD | |
| SCHEMBL988048 | 0.67 | THRB (0.57) | THRBTP53MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |