SCHEMBL21119612

SCHEMBL21119612

c1ccc(-c2ccc3ccc4ccc(-c5ccc(-c6ccc7c(ccc8oc9ccccc9c87)c6)cc5)nc4c3n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.40
PLA2G2A P14555 4/20 0.39
PLA2G4A P47712 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
ABCG2 Q9UNQ0 3/20 0.37
CYP1A1 P04798 1/20 0.37
CYP1A2 P05177 1/20 0.37
FYN P06241 1/20 0.37
MAPK3 P27361 1/20 0.37
AHR P35869 1/20 0.37
PAX8 Q06710 1/20 0.37
GAA P10253 1/20 0.37
CASP3 P42574 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
HCRTR1 O43613 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 1/20 0.36
ESR1 P03372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21119623 0.90 TDP1 (0.35) PGRPLA2G2APLA2G4AL3MBTL1TDP1
SCHEMBL21119619 0.90 MAPK1 (0.38) PGRPLA2G2APLA2G4AL3MBTL1TDP1
SCHEMBL15581888 0.90 ABCG2 (0.43) PGRL3MBTL1TDP1ABCG2CYP1A1
SCHEMBL21119580 0.89 AHR (0.38) L3MBTL1TDP1CYP1A2AHRGAA
SCHEMBL21119949 0.89 MAPK1 (0.37) PGRPLA2G2APLA2G4AL3MBTL1TDP1
SCHEMBL15581883 0.88 ABCG2 (0.44) PGRPLA2G2APLA2G4AL3MBTL1TDP1
SCHEMBL20042373 0.87 CASP3 (0.41) PGRPLA2G2APLA2G4AL3MBTL1TDP1
SCHEMBL21119961 0.87 TDO2 (0.38) L3MBTL1TDP1GAAHCRTR1MAPK1
SCHEMBL15581739 0.87 PLA2G2A (0.46) PGRPLA2G2APLA2G4AL3MBTL1TDP1
SCHEMBL15581809 0.87 PLA2G2A (0.46) PGRPLA2G2APLA2G4AL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11522139-B2 Organic light emitting diode LG DISPLAY CO., LTD. (KR) 2022-12-06 US disclosed
US-20190207123-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2019-07-04 US disclosed