Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.61 |
| ▸ | CNR2 | P34972 | 5/20 | 0.49 |
| ▸ | CNR1 | P21554 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709665 | 0.86 | CNR2 (0.60) | DNM1CNR2CNR1ALDH1A1TSHR | |
| SCHEMBL10494939 | 0.83 | DNM1 (0.47) | DNM1CNR2CNR1ALDH1A1TSHR | |
| SCHEMBL223184 | 0.82 | CNR2 (0.52) | DNM1CNR2CNR1ALDH1A1TSHR | |
| SCHEMBL548775 | 0.82 | CNR2 (0.52) | DNM1CNR2CNR1ALDH1A1TSHR | |
| SCHEMBL10397170 | 0.80 | CNR2 (0.50) | DNM1CNR2CNR1ALDH1A1TSHR | |
| SCHEMBL20040004 | 0.80 | DNM1 (0.63) | DNM1CNR2CNR1ALDH1A1HTT | |
| SCHEMBL157672 | 0.80 | CNR2 (0.50) | DNM1CNR2CNR1ALDH1A1TSHR | |
| SCHEMBL17881327 | 0.80 | CNR2 (0.50) | DNM1CNR2CNR1ALDH1A1TSHR | |
| SCHEMBL24302354 | 0.80 | CNR1 (0.82) | DNM1CNR2CNR1ALDH1A1MAPT | |
| SCHEMBL88033 | 0.79 | CNR2 (0.69) | DNM1CNR2CNR1ALDH1A1LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233862-B1 | IMIDAZOPYRIDAZINE DERIVATIVES AS PI3KBETA INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-07-03 | — | — | EP | disclosed |