SCHEMBL21124

SCHEMBL21124

Nc1ccc2c3c(cccc13)C(=O)NC2=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 1.00
USP2 O75604 8/20 1.00
MEN1 O00255 8/20 1.00
MAPT P10636 6/20 1.00
RGS12 O14924 3/20 1.00
RECQL P46063 3/20 1.00
NPSR1 Q6W5P4 3/20 1.00
PARP1 P09874 2/20 1.00
THRB P10828 2/20 1.00
CYP1A2 P05177 1/20 1.00
POLB P06746 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2C9 P11712 1/20 1.00
APEX1 P27695 1/20 1.00
CASP1 P29466 1/20 1.00
BRCA1 P38398 1/20 1.00
MTOR P42345 1/20 1.00
BLM P54132 1/20 1.00
CASP7 P55210 1/20 1.00
GNAI1 P63096 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29941362 1.00 KMT2A (1.00) KMT2AUSP2MEN1MAPTRGS12
SCHEMBL6681252 0.87 KMT2A (0.77) KMT2AUSP2MEN1MAPTRGS12
SCHEMBL11689659 0.85 USP2 (0.74) KMT2AUSP2MEN1MAPTRGS12
SCHEMBL4610799 0.85 CASP1 (0.74) KMT2AUSP2MEN1MAPTRGS12
Hydrochloric Acid SCHEMBL9078759 0.84 CASP1 (0.72) KMT2AUSP2MEN1MAPTRGS12
SCHEMBL12874092 0.82 KEAP1 (0.69) KMT2AUSP2MEN1MAPTRGS12
SCHEMBL29556131 0.78 USP2 (0.65) KMT2AUSP2MEN1MAPTRGS12
SCHEMBL5746359 0.78 MEN1 (0.65) KMT2AUSP2MEN1MAPTRGS12
SCHEMBL30516566 0.78 USP2 (0.65) KMT2AUSP2MEN1MAPTRGS12
SCHEMBL1025154 0.78 USP2 (0.65) KMT2AUSP2MEN1MAPTRGS12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2585 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115581847-B Photodynamic balloon catheter system 杭州矩正医疗科技有限公司 2026-05-19 CN claimed
EP-4696341-A1 MEDICAL DEVICE AND SYSTEM, AND PREPARATION METHOD Shanghai MicroPort Medical (Group) Co., Ltd. (CN) 2026-02-18 EP claimed
EP-3688277-B1 PROCESS FOR DEFINING THE LOCATIONS OF A PLURALITY OF WELLS IN A FIELD, RELATED SYSTEM AND COMPUTER PROGRAM PRODUCT TOTALENERGIES ONETECH (FR) 2025-02-19 EP claimed
US-12178827-B2 Nicotinyl riboside compounds and their uses MITOPOWER LLC (US) 2024-12-31 US claimed
WO-2024244915-A1 MEDICAL DEVICE AND SYSTEM, AND PREPARATION METHOD 上海微创医疗器械(集团)有限公司 2024-12-05 WO claimed
EP-4228940-B1 METHOD FOR CONTROLLING A BRAKING SYSTEM WITH B-B-W TECHNOLOGY FOR THE DISTRIBUTION OF BRAKING FORCES FOR PARKING A VEHICLE AND SYSTEM THEREOF BREMBO SPA (IT) 2024-09-18 EP claimed
EP-4419094-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS Edison Oncology (US) 2024-08-28 EP claimed
CN-112457486-B Polyamides with in-backbone light absorbers and related methods 施乐公司 2024-08-27 CN claimed
EP-3840053-B1 DISPLAY DEVICE SAMSUNG DISPLAY CO LTD (KR) 2024-08-07 EP claimed
CN-112457484-B Particles comprising polyamides with in-backbone light absorbers and related methods 施乐公司 2024-06-25 CN claimed
EP-0445926-B1 Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation MILLIKEN RES CORP (US) 1996-08-21 EP claimed
EP-0638309-A1 Substances inhibiting proteic adp ribosilation suitable to prevent the diabetes mellitus complications ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.p.A. (IT) 1995-02-15 EP claimed
US-5279967-A Using fluorophore label NALCO CHEMICAL COMPANY (US) 1994-01-18 US claimed
US-5094740-A TWO-DIMENSIONAL ELECTROPHORETIC SEPARATION OF CARBOHYDRATES GLYCOMED, INC. (US) 1992-03-10 US claimed
EP-0187076-B1 FLUORESCENT COMPOUNDS, (AMINO-4) NAPHTHALIMIDE DERIVATIVES, THEIR USE IN IMMUNOLOGICAL DETERMINATIONS OF FLUORESCENCE POLARIZATION Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1991-09-18 EP claimed
EP-0445926-A2 Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation MILLIKEN RESEARCH CORPORATION (US) 1991-09-11 EP claimed
WO-1991012275-A1 TWO-DIMENSIONAL ELECTROPHORETIC SEPARATION OF CARBOHYDRATES GLYCOMED INCORPORATED (US) 1991-08-22 WO claimed
EP-0400038-A1 WATER-DISSIPATABLE POLYESTER AND POLYESTER-AMIDES CONTAINING COPOLYMERIZED COLORANTS EASTMAN CHEMICAL COMPANY (US) 1990-12-05 EP claimed
WO-1989007118-A1 WATER-DISSIPATABLE POLYESTER AND POLYESTER-AMIDES CONTAINING COPOLYMERIZED COLORANTS EASTMAN KODAK COMPANY (US) 1989-08-10 WO claimed
US-4804719-A PRINTING INKS; COATINGS; HEAT AND COLD RESISTANCE EASTMAN KODAK COMPANY (US) 1989-02-14 US claimed